Trait
SNPs associated with Allergic rhinitis
75 genetic variants across 24 genes have been associated with Allergic rhinitis in published research. Key genes include ABO, ALOX15, ATXN2.
Associated variants75 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs7775228 | HLA-DQB1 | Increased allergic rhinitis and grass sensitization risk | Meta-analysis |
| rs11236797 | — | GWAS association (p=5.0e-32) | Major Consortium Study |
| rs7728912 | — | GWAS association (p=5.0e-26) | Major Consortium Study |
| rs72823641 | IL1RL1 | GWAS association (p=2.0e-25) | Major Consortium Study |
| rs66819621 | — | GWAS association (p=2.0e-25) | Major Consortium Study |
| rs7744020 | HLA-DQB1-AS1 | GWAS association (p=4.0e-25) | Major Consortium Study |
| rs34290285 | — | GWAS association (p=3.0e-24) | Major Consortium Study |
| rs34463936 | — | GWAS association (p=8.0e-19) | Major Consortium Study |
| rs7848215 | — | GWAS association (p=5.0e-18) | Major Consortium Study |
| rs1888909 | — | GWAS association (p=9.0e-18) | Major Consortium Study |
| rs112401631 | — | GWAS association (p=3.0e-17) | Major Consortium Study |
| rs891058 | — | GWAS association (p=3.0e-16) | Major Consortium Study |
| rs10975479 | — | GWAS association (p=8.0e-16) | Major Consortium Study |
| rs17293632 | SMAD3 | GWAS association (p=9.0e-16) | Major Consortium Study |
| rs1904522 | — | GWAS association (p=5.0e-15) | Major Consortium Study |
| rs12935657 | — | GWAS association (p=8.0e-15) | Major Consortium Study |
| rs72743461 | SMAD3 | GWAS association (p=9.0e-13) | Major Consortium Study |
| rs2601191 | — | GWAS association (p=6.0e-12) | Major Consortium Study |
| rs13107325 | SLC39A8 | GWAS association (p=4.0e-11) | Major Consortium Study |
| rs6094570 | — | GWAS association (p=5.0e-11) | Major Consortium Study |
| rs4921290 | MIR3142HG | GWAS association (p=6.0e-11) | Major Consortium Study |
| rs962993 | — | GWAS association (p=6.0e-11) | Major Consortium Study |
| rs6738825 | PLCL1 | GWAS association (p=2.0e-10) | Major Consortium Study |
| rs2988277 | — | GWAS association (p=3.0e-10) | Major Consortium Study |
| rs2070901 | FCER1G | GWAS association (p=4.0e-10) | Major Consortium Study |
| rs2640564 | — | GWAS association (p=1.0e-09) | Major Consortium Study |
| rs34210653 | ALOX15 | GWAS association (p=2.0e-09) | Major Consortium Study |
| rs12920150 | — | GWAS association (p=4.0e-09) | Major Consortium Study |
| rs79180837 | ITGB8 | GWAS association (p=7.0e-09) | Major Consortium Study |
| rs597808 | ATXN2 | GWAS association (p=2.0e-08) | Major Consortium Study |
| rs491087 | — | GWAS association (p=2.0e-08) | Major Consortium Study |
| rs1555926 | — | GWAS association (p=2.0e-08) | Major Consortium Study |
| rs7717955 | — | GWAS association (p=4.0e-32) | Large GWAS |
| rs34004019 | HLA-DQB1-AS1 | GWAS association (p=1.0e-30) | Large GWAS |
| rs950881 | IL1RL1 | GWAS association (p=2.0e-30) | Large GWAS |
| rs5743618 | TLR1 | GWAS association (p=4.0e-27) | Large GWAS |
| rs1438673 | — | GWAS association (p=3.0e-26) | Large GWAS |
| rs7936323 | — | GWAS association (p=7.0e-24) | Large GWAS |
| rs28361986 | — | GWAS association (p=2.0e-23) | Large GWAS |
| rs2070902 | — | GWAS association (p=6.0e-19) | Large GWAS |
| rs2428494 | HLA-B | GWAS association (p=7.0e-19) | Large GWAS |
| rs1504215 | — | GWAS association (p=2.0e-18) | Large GWAS |
| rs11644510 | — | GWAS association (p=2.0e-17) | Large GWAS |
| rs12939457 | ZPBP2 | GWAS association (p=2.0e-17) | Large GWAS |
| rs2519093 | ABO | GWAS association (p=3.0e-16) | Large GWAS |
| rs12509403 | NFKB1 | GWAS association (p=1.0e-15) | Large GWAS |
| rs148505069 | — | GWAS association (p=3.0e-15) | Large GWAS |
| rs2815765 | LOC105378797 | GWAS association (p=9.0e-15) | Large GWAS |
| rs111371454 | — | GWAS association (p=1.0e-14) | Large GWAS |
| rs13395467 | — | GWAS association (p=1.0e-14) | Large GWAS |
| rs9775039 | — | GWAS association (p=2.0e-14) | Large GWAS |
| rs9648346 | JAZF1 | GWAS association (p=3.0e-14) | Large GWAS |
| rs2164068 | PLCL1 | GWAS association (p=4.0e-14) | Large GWAS |
| rs35350651 | — | GWAS association (p=6.0e-14) | Large GWAS |
| rs2030519 | — | GWAS association (p=2.0e-13) | Large GWAS |
| rs62257549 | DCAF1 | GWAS association (p=2.0e-13) | Large GWAS |
| rs11671925 | — | GWAS association (p=6.0e-13) | Large GWAS |
| rs11677002 | — | GWAS association (p=7.0e-13) | Large GWAS |
| rs11256017 | — | GWAS association (p=3.0e-12) | Large GWAS |
| rs17294280 | SMAD3 | GWAS association (p=6.0e-12) | Large GWAS |
| rs2461475 | SPPL3 | GWAS association (p=4.0e-11) | Large GWAS |
| rs7328203 | — | GWAS association (p=1.0e-10) | Large GWAS |
| rs6738964 | — | GWAS association (p=2.0e-10) | Large GWAS |
| rs7824993 | — | GWAS association (p=2.0e-10) | Large GWAS |
| rs9282864 | SULT1A1 | GWAS association (p=5.0e-10) | Large GWAS |
| rs11169225 | — | GWAS association (p=5.0e-10) | Large GWAS |
| rs13166760 | — | GWAS association (p=6.0e-10) | Large GWAS |
| rs9687749 | RAD50 | GWAS association (p=2.0e-09) | Large GWAS |
| rs2160203 | IL1RL1 | GWAS association (p=3.0e-09) | Large GWAS |
| rs61977073 | — | GWAS association (p=6.0e-09) | Large GWAS |
| rs2399472 | — | GWAS association (p=2.0e-08) | Large GWAS |
| rs4711207 | ZNRD1ASP | GWAS association (p=2.0e-08) | Large GWAS |
| rs6470578 | — | GWAS association (p=4.0e-08) | Large GWAS |
| rs3787184 | — | GWAS association (p=5.0e-08) | Large GWAS |
| rs7216389 | GSDMB | Increased risk of allergic rhinitis | Candidate gene study |
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.