rs778603

This variant is located in the TMCO6 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

thalamus volume

Elvsåshagen T et al. “The genetic architecture of the human thalamus and its overlap with ten common brain disorders.” Nature Communications 12(1):2909 (2021)

Allele A

OR 0.05

p 1.0e-9

N 30,114

Large GWAS

European

About TMCO6

Predicted to enable nuclear import signal receptor activity. Predicted to be involved in protein import into nucleus. Predicted to be located in membrane. [provided by Alliance of Genome Resources, Jul 2025]

View all TMCO6 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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