TMCO6
transmembrane and coiled-coil domains 6
Summary
Predicted to enable nuclear import signal receptor activity. Predicted to be involved in protein import into nucleus. Predicted to be located in membrane. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants34 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs2569176 | 5:139,986,317 | A/G | upstream gene variant | — |
| rs2569178 | 5:139,992,171 | G/T | — | — |
| rs2569181 | 5:139,997,812 | C/T | intergenic variant | — |
| rs778603 | 5:139,998,807 | A/C | — | — |
| rs778599 | 5:140,001,761 | G/A | intergenic variant | — |
| rs60745418 | 5:140,006,267 | C/T | intergenic variant | — |
| rs112800995 | 5:140,007,630 | G/T | — | — |
| rs5744438 | 5:140,017,868 | G/C | upstream gene variant | — |
| rs4912717 | 5:140,018,235 | G/C | — | — |
| rs1360228803 | 5:140,019,119 | A/G | — | uncertain significance |
| rs775506005 | 5:140,019,403 | G/A | — | likely benign |
| rs2481075334 | 5:140,019,404 | G/A | — | uncertain significance |
| rs1443016633 | 5:140,019,434 | G/A | — | uncertain significance |
| rs751824549 | 5:140,021,076 | G/A | — | — |
| rs201570076 | 5:140,021,265 | C/T | — | uncertain significance |
| rs372158124 | 5:140,021,278 | G/A | — | uncertain significance |
| rs2481087718 | 5:140,021,301 | G/C | — | uncertain significance |
| rs749443240 | 5:140,021,364 | C/T | — | uncertain significance |
| rs2481089200 | 5:140,021,462 | G/A | — | uncertain significance |
| rs775962744 | 5:140,021,465 | A/G | — | uncertain significance |
| rs753784715 | 5:140,021,528 | C/T | — | uncertain significance |
| rs2481090155 | 5:140,021,549 | C/G | — | uncertain significance |
| rs528303205 | 5:140,021,933 | G/A | — | uncertain significance |
| rs781676399 | 5:140,021,945 | G/A | — | uncertain significance |
| rs2481094053 | 5:140,021,959 | G/C | — | uncertain significance |
| rs199968038 | 5:140,022,177 | C/G | — | uncertain significance |
| rs201116062 | 5:140,022,212 | G/C | — | uncertain significance |
| rs769270415 | 5:140,022,530 | T/C | — | uncertain significance |
| rs1371267115 | 5:140,023,180 | G/C | — | uncertain significance |
| rs368360736 | 5:140,023,456 | G/A | — | uncertain significance |
| rs370199625 | 5:140,023,765 | G/A | — | uncertain significance |
| rs767528766 | 5:140,024,259 | T/G | — | likely benign |
| rs186700961 | 5:140,024,272 | G/A | — | uncertain significance |
| rs768631054 | 5:140,024,630 | G/C | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.