rs78074706

This is a protein-altering variant in the ANKS3 gene.

GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

high density lipoprotein cholesterol measurement

Liu DJ et al. Exome-wide association study of plasma lipids in >300,000 individuals. Nature Genetics 49(12):1758-1766 (2017)
Allele A
OR
β 0.057
p 2.0e-9
N 237,050
Large GWAS
European

About ANKS3

Predicted to be located in cytoplasm. Predicted to be active in cilium. [provided by Alliance of Genome Resources, Jul 2025]

View all ANKS3 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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