rs7815955
This is a intergenic variant variant in the GSDMC gene.
▶GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
health trait
Schoeler T et al. “Combining cross-sectional and longitudinal genomic approaches to identify determinants of cognitive and physical decline.” Nature Communications 16(1):4524 (2025)
Allele A
OR 0.02
p 3.0e-48
N 405,979
Large GWAS
European
body height
Chiou JS et al. “Your height affects your health: genetic determinants and health-related outcomes in Taiwan.” Bmc Medicine 20(1):250 (2022)
Allele A
OR 0.04
p 1.0e-13
N 67,452
Large GWAS
East Asian
About GSDMC
Enables wide pore channel activity. Involved in pyroptotic inflammatory response. Located in cytoplasm. Is active in plasma membrane. [provided by Alliance of Genome Resources, Jul 2025]
View all GSDMC variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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