rs781742545

This variant is located in the SCN10A gene.

▶

ClinVar annotation

Likely Benign★★★☆
2 submitters1 publication

Brugada syndrome; Cardiovascular phenotype

View on ClinVar →

About SCN10A

The protein encoded by this gene is a tetrodotoxin-resistant voltage-gated sodium channel alpha subunit. The properties of the channel formed by the encoded transmembrane protein can be altered by interaction with different beta subunits. This protein may be involved in the onset of pain associated with peripheral neuropathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]

View all SCN10A variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

Community Wiki

No community notes yet for this variant. Sign in to start one.

Comments

Sign in to join the discussion.

Loading comments…