rs7829127
This is a intron variant variant in the ZMAT4 gene.
▶GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
refractive error, age at onset, Myopia
Tedja MS et al. “Genome-wide association meta-analysis highlights light-induced signaling as a driver for refractive error.” Nature Genetics 50(6):834-848 (2018)
Allele A
OR 10.91
p 1.0e-27
N 170,420
Meta-analysisLarge GWAS
multi-ancestry
age at onset, Myopia
Tedja MS et al. “Genome-wide association meta-analysis highlights light-induced signaling as a driver for refractive error.” Nature Genetics 50(6):834-848 (2018)
Allele A
OR 0.09
p 8.0e-26
N 104,293
Meta-analysisLarge GWAS
European
Abnormality of refraction
Verhoeven VJ et al. “Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia.” Nature Genetics 45(3):314-8 (2013)
Allele G
OR 0.12
p 4.0e-10
N 45,758
Large GWAS
multi-ancestry
About ZMAT4
Enables identical protein binding activity. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Jul 2025]
View all ZMAT4 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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