Trait
SNPs associated with refractive error, age at onset, Myopia
135 genetic variants across 46 genes have been associated with refractive error, age at onset, Myopia in published research. Key genes include AMOTL2, ANTXR2, BMP4.
Associated variants135 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs12193446 | LAMA2 | GWAS association (p=4.0e-84) | Meta-analysis |
| rs524952 | — | GWAS association (p=2.0e-65) | Meta-analysis |
| rs7744813 | KCNQ5 | GWAS association (p=5.0e-48) | Meta-analysis |
| rs11602008 | — | GWAS association (p=2.0e-44) | Meta-analysis |
| rs3138141 | RDH5 | GWAS association (p=2.0e-43) | Meta-analysis |
| rs10500355 | RBFOX1 | GWAS association (p=6.0e-43) | Meta-analysis |
| rs72621438 | — | GWAS association (p=2.0e-39) | Meta-analysis |
| rs1550094 | PRSS56 | GWAS association (p=4.0e-37) | Meta-analysis |
| rs2908972 | — | GWAS association (p=9.0e-29) | Meta-analysis |
| rs7829127 | ZMAT4 | GWAS association (p=1.0e-27) | Meta-analysis |
| rs6495367 | — | GWAS association (p=2.0e-24) | Meta-analysis |
| rs11145465 | TJP2 | GWAS association (p=1.0e-21) | Meta-analysis |
| rs1649068 | — | GWAS association (p=4.0e-21) | Meta-analysis |
| rs7692381 | — | GWAS association (p=6.0e-21) | Meta-analysis |
| rs36024104 | — | GWAS association (p=1.0e-19) | Meta-analysis |
| rs56075542 | — | GWAS association (p=2.0e-19) | Meta-analysis |
| rs7895108 | — | GWAS association (p=8.0e-19) | Meta-analysis |
| rs7456039 | — | GWAS association (p=1.0e-18) | Meta-analysis |
| rs7624084 | — | GWAS association (p=1.0e-18) | Meta-analysis |
| rs1556867 | — | GWAS association (p=1.0e-18) | Meta-analysis |
| rs62070229 | H2BN1 | GWAS association (p=1.0e-17) | Meta-analysis |
| rs2855530 | BMP4 | GWAS association (p=1.0e-17) | Meta-analysis |
| rs7662551 | — | GWAS association (p=1.0e-17) | Meta-analysis |
| rs9517964 | — | GWAS association (p=4.0e-17) | Meta-analysis |
| rs1954761 | GRIA4 | GWAS association (p=5.0e-17) | Meta-analysis |
| rs745480 | LRIT2 | GWAS association (p=9.0e-17) | Meta-analysis |
| rs2573081 | PDE11A | GWAS association (p=2.0e-16) | Meta-analysis |
| rs17428076 | — | GWAS association (p=3.0e-16) | Meta-analysis |
| rs12667032 | DPP6 | GWAS association (p=1.0e-15) | Meta-analysis |
| rs2225986 | — | GWAS association (p=2.0e-15) | Meta-analysis |
| rs1207782 | — | GWAS association (p=2.0e-15) | Meta-analysis |
| rs72826094 | — | GWAS association (p=3.0e-15) | Meta-analysis |
| rs297593 | GPD2 | GWAS association (p=5.0e-15) | Meta-analysis |
| rs5442 | GNB3 | GWAS association (p=5.0e-15) | Meta-analysis |
| rs10880855 | — | GWAS association (p=7.0e-15) | Meta-analysis |
| rs2155413 | — | GWAS association (p=9.0e-15) | Meta-analysis |
| rs12405776 | — | GWAS association (p=1.0e-14) | Meta-analysis |
| rs2150458 | — | GWAS association (p=1.0e-14) | Meta-analysis |
| rs12898755 | — | GWAS association (p=5.0e-14) | Meta-analysis |
| rs7122817 | DSCAML1 | GWAS association (p=6.0e-14) | Meta-analysis |
| rs11178469 | PTPRR | GWAS association (p=1.0e-13) | Meta-analysis |
| rs10511652 | — | GWAS association (p=2.0e-13) | Meta-analysis |
| rs11101263 | FRMPD2 | GWAS association (p=2.0e-13) | Meta-analysis |
| rs11118367 | — | GWAS association (p=3.0e-13) | Meta-analysis |
| rs1858001 | LOC107985251 | GWAS association (p=3.0e-13) | Meta-analysis |
| rs9395623 | — | GWAS association (p=4.0e-13) | Meta-analysis |
| rs284816 | — | GWAS association (p=6.0e-13) | Meta-analysis |
| rs4793501 | — | GWAS association (p=6.0e-13) | Meta-analysis |
| rs12965607 | MYO5B | GWAS association (p=2.0e-12) | Meta-analysis |
| rs7747 | ANTXR2 | GWAS association (p=2.0e-12) | Meta-analysis |
| rs12451582 | — | GWAS association (p=2.0e-12) | Meta-analysis |
| rs80253120 | — | GWAS association (p=3.0e-12) | Meta-analysis |
| rs7968679 | — | GWAS association (p=4.0e-12) | Meta-analysis |
| rs11202736 | RNLS | GWAS association (p=5.0e-12) | Meta-analysis |
| rs11088317 | — | GWAS association (p=5.0e-12) | Meta-analysis |
| rs10853531 | — | GWAS association (p=6.0e-12) | Meta-analysis |
| rs72655575 | — | GWAS association (p=7.0e-12) | Meta-analysis |
| rs12998513 | — | GWAS association (p=7.0e-12) | Meta-analysis |
| rs1790165 | NTM | GWAS association (p=7.0e-12) | Meta-analysis |
| rs7042950 | RORB | GWAS association (p=1.0e-11) | Meta-analysis |
| rs511217 | — | GWAS association (p=1.0e-11) | Meta-analysis |
| rs1150687 | — | GWAS association (p=1.0e-11) | Meta-analysis |
| rs56055503 | — | GWAS association (p=2.0e-11) | Meta-analysis |
| rs9681162 | — | GWAS association (p=2.0e-11) | Meta-analysis |
| rs11589487 | — | GWAS association (p=3.0e-11) | Meta-analysis |
| rs1454776 | LOC107986064 | GWAS association (p=3.0e-11) | Meta-analysis |
| rs2166181 | — | GWAS association (p=3.0e-11) | Meta-analysis |
| rs10187371 | ZEB2 | GWAS association (p=5.0e-11) | Meta-analysis |
| rs4687586 | — | GWAS association (p=6.0e-11) | Meta-analysis |
| rs11160044 | NDUFB1 | GWAS association (p=7.0e-11) | Meta-analysis |
| rs1064583 | COL10A1 | GWAS association (p=7.0e-11) | Meta-analysis |
| rs2753462 | — | GWAS association (p=8.0e-11) | Meta-analysis |
| rs41393947 | — | GWAS association (p=1.0e-10) | Meta-analysis |
| rs6753137 | — | GWAS association (p=2.0e-10) | Meta-analysis |
| rs1969091 | — | GWAS association (p=2.0e-10) | Meta-analysis |
| rs35337422 | — | GWAS association (p=2.0e-10) | Meta-analysis |
| rs116226959 | — | GWAS association (p=3.0e-10) | Meta-analysis |
| rs837323 | — | GWAS association (p=3.0e-10) | Meta-analysis |
| rs11654644 | — | GWAS association (p=3.0e-10) | Meta-analysis |
| rs17382981 | — | GWAS association (p=3.0e-10) | Meta-analysis |
| rs1359543 | RCBTB1 | GWAS association (p=3.0e-10) | Meta-analysis |
| rs28891973 | — | GWAS association (p=4.0e-10) | Meta-analysis |
| rs3213636 | — | GWAS association (p=4.0e-10) | Meta-analysis |
| rs9516194 | — | GWAS association (p=4.0e-10) | Meta-analysis |
| rs12883788 | — | GWAS association (p=4.0e-10) | Meta-analysis |
| rs9388766 | — | GWAS association (p=5.0e-10) | Meta-analysis |
| rs17125093 | — | GWAS association (p=5.0e-10) | Meta-analysis |
| rs60884546 | VIPR2 | GWAS association (p=5.0e-10) | Meta-analysis |
| rs1555075 | — | GWAS association (p=5.0e-10) | Meta-analysis |
| rs11802995 | — | GWAS association (p=6.0e-10) | Meta-analysis |
| rs4764038 | — | GWAS association (p=6.0e-10) | Meta-analysis |
| rs7337610 | FLT1 | GWAS association (p=8.0e-10) | Meta-analysis |
| rs2229742 | NRIP1 | GWAS association (p=9.0e-10) | Meta-analysis |
| rs478304 | — | GWAS association (p=1.0e-09) | Meta-analysis |
| rs2303635 | AMOTL2 | GWAS association (p=1.0e-09) | Meta-analysis |
| rs117735470 | — | GWAS association (p=1.0e-09) | Meta-analysis |
| rs4808962 | GATAD2A | GWAS association (p=1.0e-09) | Meta-analysis |
| rs10458138 | — | GWAS association (p=1.0e-09) | Meta-analysis |
| rs144370238 | — | GWAS association (p=1.0e-09) | Meta-analysis |
| rs10760673 | — | GWAS association (p=2.0e-09) | Meta-analysis |
Showing the top 100 of 135 variants by evidence strength.
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.