Trait

SNPs associated with refractive error, age at onset, Myopia

135 genetic variants across 46 genes have been associated with refractive error, age at onset, Myopia in published research. Key genes include AMOTL2, ANTXR2, BMP4.

Associated variants135 total

rsidGeneEffectEvidence
rs12193446LAMA2GWAS association (p=4.0e-84)Meta-analysis
rs524952—GWAS association (p=2.0e-65)Meta-analysis
rs7744813KCNQ5GWAS association (p=5.0e-48)Meta-analysis
rs11602008—GWAS association (p=2.0e-44)Meta-analysis
rs3138141RDH5GWAS association (p=2.0e-43)Meta-analysis
rs10500355RBFOX1GWAS association (p=6.0e-43)Meta-analysis
rs72621438—GWAS association (p=2.0e-39)Meta-analysis
rs1550094PRSS56GWAS association (p=4.0e-37)Meta-analysis
rs2908972—GWAS association (p=9.0e-29)Meta-analysis
rs7829127ZMAT4GWAS association (p=1.0e-27)Meta-analysis
rs6495367—GWAS association (p=2.0e-24)Meta-analysis
rs11145465TJP2GWAS association (p=1.0e-21)Meta-analysis
rs1649068—GWAS association (p=4.0e-21)Meta-analysis
rs7692381—GWAS association (p=6.0e-21)Meta-analysis
rs36024104—GWAS association (p=1.0e-19)Meta-analysis
rs56075542—GWAS association (p=2.0e-19)Meta-analysis
rs7895108—GWAS association (p=8.0e-19)Meta-analysis
rs7456039—GWAS association (p=1.0e-18)Meta-analysis
rs7624084—GWAS association (p=1.0e-18)Meta-analysis
rs1556867—GWAS association (p=1.0e-18)Meta-analysis
rs62070229H2BN1GWAS association (p=1.0e-17)Meta-analysis
rs2855530BMP4GWAS association (p=1.0e-17)Meta-analysis
rs7662551—GWAS association (p=1.0e-17)Meta-analysis
rs9517964—GWAS association (p=4.0e-17)Meta-analysis
rs1954761GRIA4GWAS association (p=5.0e-17)Meta-analysis
rs745480LRIT2GWAS association (p=9.0e-17)Meta-analysis
rs2573081PDE11AGWAS association (p=2.0e-16)Meta-analysis
rs17428076—GWAS association (p=3.0e-16)Meta-analysis
rs12667032DPP6GWAS association (p=1.0e-15)Meta-analysis
rs2225986—GWAS association (p=2.0e-15)Meta-analysis
rs1207782—GWAS association (p=2.0e-15)Meta-analysis
rs72826094—GWAS association (p=3.0e-15)Meta-analysis
rs297593GPD2GWAS association (p=5.0e-15)Meta-analysis
rs5442GNB3GWAS association (p=5.0e-15)Meta-analysis
rs10880855—GWAS association (p=7.0e-15)Meta-analysis
rs2155413—GWAS association (p=9.0e-15)Meta-analysis
rs12405776—GWAS association (p=1.0e-14)Meta-analysis
rs2150458—GWAS association (p=1.0e-14)Meta-analysis
rs12898755—GWAS association (p=5.0e-14)Meta-analysis
rs7122817DSCAML1GWAS association (p=6.0e-14)Meta-analysis
rs11178469PTPRRGWAS association (p=1.0e-13)Meta-analysis
rs10511652—GWAS association (p=2.0e-13)Meta-analysis
rs11101263FRMPD2GWAS association (p=2.0e-13)Meta-analysis
rs11118367—GWAS association (p=3.0e-13)Meta-analysis
rs1858001LOC107985251GWAS association (p=3.0e-13)Meta-analysis
rs9395623—GWAS association (p=4.0e-13)Meta-analysis
rs284816—GWAS association (p=6.0e-13)Meta-analysis
rs4793501—GWAS association (p=6.0e-13)Meta-analysis
rs12965607MYO5BGWAS association (p=2.0e-12)Meta-analysis
rs7747ANTXR2GWAS association (p=2.0e-12)Meta-analysis
rs12451582—GWAS association (p=2.0e-12)Meta-analysis
rs80253120—GWAS association (p=3.0e-12)Meta-analysis
rs7968679—GWAS association (p=4.0e-12)Meta-analysis
rs11202736RNLSGWAS association (p=5.0e-12)Meta-analysis
rs11088317—GWAS association (p=5.0e-12)Meta-analysis
rs10853531—GWAS association (p=6.0e-12)Meta-analysis
rs72655575—GWAS association (p=7.0e-12)Meta-analysis
rs12998513—GWAS association (p=7.0e-12)Meta-analysis
rs1790165NTMGWAS association (p=7.0e-12)Meta-analysis
rs7042950RORBGWAS association (p=1.0e-11)Meta-analysis
rs511217—GWAS association (p=1.0e-11)Meta-analysis
rs1150687—GWAS association (p=1.0e-11)Meta-analysis
rs56055503—GWAS association (p=2.0e-11)Meta-analysis
rs9681162—GWAS association (p=2.0e-11)Meta-analysis
rs11589487—GWAS association (p=3.0e-11)Meta-analysis
rs1454776LOC107986064GWAS association (p=3.0e-11)Meta-analysis
rs2166181—GWAS association (p=3.0e-11)Meta-analysis
rs10187371ZEB2GWAS association (p=5.0e-11)Meta-analysis
rs4687586—GWAS association (p=6.0e-11)Meta-analysis
rs11160044NDUFB1GWAS association (p=7.0e-11)Meta-analysis
rs1064583COL10A1GWAS association (p=7.0e-11)Meta-analysis
rs2753462—GWAS association (p=8.0e-11)Meta-analysis
rs41393947—GWAS association (p=1.0e-10)Meta-analysis
rs6753137—GWAS association (p=2.0e-10)Meta-analysis
rs1969091—GWAS association (p=2.0e-10)Meta-analysis
rs35337422—GWAS association (p=2.0e-10)Meta-analysis
rs116226959—GWAS association (p=3.0e-10)Meta-analysis
rs837323—GWAS association (p=3.0e-10)Meta-analysis
rs11654644—GWAS association (p=3.0e-10)Meta-analysis
rs17382981—GWAS association (p=3.0e-10)Meta-analysis
rs1359543RCBTB1GWAS association (p=3.0e-10)Meta-analysis
rs28891973—GWAS association (p=4.0e-10)Meta-analysis
rs3213636—GWAS association (p=4.0e-10)Meta-analysis
rs9516194—GWAS association (p=4.0e-10)Meta-analysis
rs12883788—GWAS association (p=4.0e-10)Meta-analysis
rs9388766—GWAS association (p=5.0e-10)Meta-analysis
rs17125093—GWAS association (p=5.0e-10)Meta-analysis
rs60884546VIPR2GWAS association (p=5.0e-10)Meta-analysis
rs1555075—GWAS association (p=5.0e-10)Meta-analysis
rs11802995—GWAS association (p=6.0e-10)Meta-analysis
rs4764038—GWAS association (p=6.0e-10)Meta-analysis
rs7337610FLT1GWAS association (p=8.0e-10)Meta-analysis
rs2229742NRIP1GWAS association (p=9.0e-10)Meta-analysis
rs478304—GWAS association (p=1.0e-09)Meta-analysis
rs2303635AMOTL2GWAS association (p=1.0e-09)Meta-analysis
rs117735470—GWAS association (p=1.0e-09)Meta-analysis
rs4808962GATAD2AGWAS association (p=1.0e-09)Meta-analysis
rs10458138—GWAS association (p=1.0e-09)Meta-analysis
rs144370238—GWAS association (p=1.0e-09)Meta-analysis
rs10760673—GWAS association (p=2.0e-09)Meta-analysis

Showing the top 100 of 135 variants by evidence strength.

Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.

refractive error, age at onset, Myopia — SNPs & genetic associations — Gene Wizard