CLU
clusterin
Summary
The protein encoded by this gene is a secreted chaperone that can under some stress conditions also be found in the cell cytosol. It has been suggested to be involved in several basic biological events such as cell death, tumor progression, and neurodegenerative disorders. Alternate splicing results in both coding and non-coding variants.[provided by RefSeq, May 2011]
Known Variants32 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs9331949 | 8:27,454,686 | T/C | regulatory region variant | — |
| rs3087554 | 8:27,455,442 | T/C | 3 prime UTR variant | — |
| rs200244739 | 8:27,455,749 | A/G | — | likely benign |
| rs144959547 | 8:27,456,003 | C/A | — | likely benign |
| rs755605617 | 8:27,456,099 | G/A | — | likely benign |
| rs151154581 | 8:27,456,126 | G/A | — | benign |
| rs13494 | 8:27,456,130 | G/A | — | benign |
| rs2279590 | 8:27,456,253 | T/G | — | — |
| rs200287772 | 8:27,457,462 | G/A | — | likely benign |
| rs9331939 | 8:27,457,477 | G/A | — | benign |
| rs9331938 | 8:27,457,479 | C/T | — | benign |
| rs9331937 | 8:27,457,507 | G/C | — | benign |
| rs149705964 | 8:27,462,461 | G/A | missense variant | — |
| rs7982 | 8:27,462,481 | A/G | synonymous variant | benign |
| rs367989790 | 8:27,462,514 | G/A | — | likely benign |
| rs751114860 | 8:27,462,565 | G/A | — | likely benign |
| rs41276297 | 8:27,462,662 | G/A | — | likely benign |
| rs530052697 | 8:27,462,706 | G/A | — | likely benign |
| rs201670453 | 8:27,462,725 | C/T | missense variant | Likely benign |
| rs781592788 | 8:27,463,863 | C/G | — | benign |
| rs150438413 | 8:27,463,906 | C/T | — | benign |
| rs11136000 | 8:27,464,519 | C/T | intron variant | — |
| rs4236673 | 8:27,464,929 | A/C | — | — |
| rs1532277 | 8:27,466,181 | T/C | regulatory region variant | — |
| rs1532278 | 8:27,466,315 | T/C | regulatory region variant | — |
| rs146277764 | 8:27,466,509 | G/A | — | likely benign |
| rs9331898 | 8:27,466,578 | G/A | — | benign |
| rs762317872 | 8:27,466,581 | C/T | — | likely benign |
| rs9331896 | 8:27,467,686 | C/A | — | — |
| rs141237968 | 8:27,468,014 | C/T | — | likely benign |
| rs756571678 | 8:27,468,029 | G/A | — | likely benign |
| rs9331888 | 8:27,468,862 | C/G | regulatory region variant | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.