AMOTL2
angiomotin like 2
Summary
Angiomotin is a protein that binds angiostatin, a circulating inhibitor of the formation of new blood vessels (angiogenesis). Angiomotin mediates angiostatin inhibition of endothelial cell migration and tube formation in vitro. The protein encoded by this gene is related to angiomotin and is a member of the motin protein family. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]
Known Variants66 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs3821705 | 3:134,077,001 | G/A | regulatory region variant | — |
| rs749660523 | 3:134,077,453 | G/A | — | uncertain significance |
| rs760059061 | 3:134,077,462 | G/T | — | uncertain significance |
| rs1212435441 | 3:134,077,474 | G/A | — | uncertain significance |
| rs371309239 | 3:134,077,525 | G/C | — | uncertain significance |
| rs531395353 | 3:134,077,556 | T/C | — | uncertain significance |
| rs746713717 | 3:134,078,260 | C/A | — | uncertain significance |
| rs368824669 | 3:134,078,278 | T/C | — | uncertain significance |
| rs371941299 | 3:134,078,996 | T/C | — | uncertain significance |
| rs201755719 | 3:134,079,011 | G/A | — | uncertain significance |
| rs151045996 | 3:134,079,019 | C/G | — | uncertain significance |
| rs140871979 | 3:134,079,028 | A/C | — | uncertain significance |
| rs550324555 | 3:134,079,051 | G/A | — | uncertain significance |
| rs753620282 | 3:134,079,066 | T/C | — | uncertain significance |
| rs762140866 | 3:134,079,101 | C/T | — | uncertain significance |
| rs561578417 | 3:134,079,173 | C/T | — | uncertain significance |
| rs750405650 | 3:134,079,174 | G/C | — | uncertain significance |
| rs766621996 | 3:134,079,191 | C/T | — | uncertain significance |
| rs547949613 | 3:134,079,194 | A/G | — | uncertain significance |
| rs137933371 | 3:134,079,198 | C/A | — | uncertain significance |
| rs35993053 | 3:134,080,370 | G/A | — | benign |
| rs764237309 | 3:134,080,454 | G/A | — | uncertain significance |
| rs774387200 | 3:134,080,500 | G/A | — | uncertain significance |
| rs770749530 | 3:134,080,512 | C/G | — | uncertain significance |
| rs1289784722 | 3:134,080,515 | C/A | — | uncertain significance |
| rs759434423 | 3:134,080,517 | C/T | — | uncertain significance |
| rs367972576 | 3:134,080,526 | C/T | — | uncertain significance |
| rs554840600 | 3:134,080,563 | C/T | — | uncertain significance |
| rs113677766 | 3:134,080,567 | A/G | — | benign |
| rs377093098 | 3:134,080,584 | C/T | — | uncertain significance |
| rs545800849 | 3:134,080,596 | G/C | — | uncertain significance |
| rs376696013 | 3:134,080,613 | C/T | — | uncertain significance |
| rs2472949988 | 3:134,080,626 | C/T | — | uncertain significance |
| rs779874351 | 3:134,080,628 | T/A | — | uncertain significance |
| rs776102853 | 3:134,084,680 | C/T | — | uncertain significance |
| rs202200117 | 3:134,085,126 | T/G | — | uncertain significance |
| rs777155262 | 3:134,085,178 | T/G | — | uncertain significance |
| rs1559800340 | 3:134,085,189 | C/A | — | uncertain significance |
| rs142974587 | 3:134,085,205 | C/T | — | uncertain significance |
| rs575761212 | 3:134,085,250 | C/T | — | uncertain significance |
| rs369381825 | 3:134,086,349 | C/T | — | uncertain significance |
| rs2303635 | 3:134,086,356 | C/A | missense variant | — |
| rs199708212 | 3:134,086,392 | G/A | — | uncertain significance |
| rs757695633 | 3:134,086,397 | T/C | — | uncertain significance |
| rs144090840 | 3:134,086,431 | C/T | — | uncertain significance |
| rs1237266812 | 3:134,086,520 | G/T | — | uncertain significance |
| rs2472962968 | 3:134,086,521 | A/T | — | uncertain significance |
| rs1331531302 | 3:134,086,529 | G/A | — | uncertain significance |
| rs180867534 | 3:134,086,539 | C/T | — | likely benign |
| rs370366782 | 3:134,089,588 | G/A | — | uncertain significance |
| rs2472969183 | 3:134,089,638 | T/C | — | uncertain significance |
| rs781488547 | 3:134,089,651 | G/T | — | uncertain significance |
| rs368269741 | 3:134,089,665 | G/A | — | uncertain significance |
| rs772645724 | 3:134,089,711 | G/A | — | uncertain significance |
| rs1219426534 | 3:134,089,717 | G/T | — | uncertain significance |
| rs764129675 | 3:134,089,755 | G/A | — | uncertain significance |
| rs143351962 | 3:134,089,758 | C/T | — | likely benign |
| rs201856617 | 3:134,089,794 | C/T | — | uncertain significance |
| rs761787826 | 3:134,089,888 | C/A | — | uncertain significance |
| rs199955100 | 3:134,089,902 | C/T | — | uncertain significance |
| rs372993151 | 3:134,089,923 | G/C | — | uncertain significance |
| rs144163944 | 3:134,090,034 | C/A | — | uncertain significance |
| rs751105132 | 3:134,090,191 | G/A | — | uncertain significance |
| rs2472971492 | 3:134,090,194 | T/A | — | uncertain significance |
| rs1266152339 | 3:134,090,253 | G/A | — | uncertain significance |
| rs1863910 | 3:134,092,058 | A/G | regulatory region variant | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.