VIPR2
vasoactive intestinal peptide receptor 2
Summary
This gene encodes a receptor for vasoactive intestinal peptide, a small neuropeptide. Vasoactive intestinal peptide is involved in smooth muscle relaxation, exocrine and endocrine secretion, and water and ion flux in lung and intestinal epithelia. Its actions are effected through integral membrane receptors associated with a guanine nucleotide binding protein which activates adenylate cyclase. [provided by RefSeq, Aug 2011]
Known Variants44 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs885863 | 7:158,820,969 | C/T | coding sequence variant | — |
| rs885861 | 7:158,821,547 | G/A | coding sequence variant | — |
| rs2730220 | 7:158,822,058 | T/G | coding sequence variant | — |
| rs374813944 | 7:158,823,347 | C/A | — | uncertain significance |
| rs753755645 | 7:158,823,356 | C/T | — | uncertain significance |
| rs548150495 | 7:158,823,368 | A/G | — | uncertain significance |
| rs150222738 | 7:158,823,385 | G/C | — | uncertain significance |
| rs138691820 | 7:158,823,395 | A/G | — | benign |
| rs1853497399 | 7:158,823,398 | G/A | — | uncertain significance |
| rs899508976 | 7:158,823,434 | G/T | — | likely benign |
| rs890738596 | 7:158,824,631 | G/T | — | uncertain significance |
| rs147214125 | 7:158,824,645 | C/T | — | likely benign |
| rs768304110 | 7:158,824,649 | G/A | — | likely benign |
| rs142898881 | 7:158,824,725 | C/T | — | likely benign |
| rs1009852870 | 7:158,824,747 | T/C | — | uncertain significance |
| rs2071625 | 7:158,825,020 | C/T | downstream gene variant | — |
| rs745321835 | 7:158,826,934 | T/A | — | uncertain significance |
| rs1853808093 | 7:158,827,309 | C/G | — | uncertain significance |
| rs1178333682 | 7:158,827,322 | G/A | — | uncertain significance |
| rs2071623 | 7:158,827,414 | T/C | downstream gene variant | — |
| rs898595582 | 7:158,828,644 | C/T | — | uncertain significance |
| rs140691706 | 7:158,828,662 | G/C | — | uncertain significance |
| rs767637413 | 7:158,829,565 | A/G | — | uncertain significance |
| rs1374930339 | 7:158,829,567 | G/C | — | uncertain significance |
| rs1182907193 | 7:158,835,746 | G/A | — | uncertain significance |
| rs3763426 | 7:158,835,804 | G/A | — | benign |
| rs2730260 | 7:158,846,929 | G/C | — | — |
| rs138307314 | 7:158,851,179 | G/A | — | uncertain significance |
| rs1330125774 | 7:158,851,200 | T/C | — | uncertain significance |
| rs2467806 | 7:158,854,214 | T/C | intron variant | — |
| rs60884546 | 7:158,874,598 | G/A | intron variant | — |
| rs533811103 | 7:158,889,595 | G/A | — | likely benign |
| rs2485917157 | 7:158,896,476 | C/T | — | uncertain significance |
| rs201357541 | 7:158,896,486 | C/T | — | uncertain significance |
| rs143947210 | 7:158,896,489 | C/T | — | likely benign |
| rs146731234 | 7:158,896,523 | C/T | — | benign |
| rs539276528 | 7:158,896,524 | G/A | — | uncertain significance |
| rs542501834 | 7:158,902,547 | G/A | — | uncertain significance |
| rs551525719 | 7:158,902,602 | C/T | — | uncertain significance |
| rs141313179 | 7:158,906,675 | A/G | intron variant | — |
| rs6459924 | 7:158,908,074 | T/C | intron variant | — |
| rs151123574 | 7:158,935,228 | T/C | — | uncertain significance |
| rs1797619371 | 7:158,937,376 | C/T | — | uncertain significance |
| rs3828966 | 7:158,937,870 | T/G | — | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.