Trait
SNPs associated with Pathological Myopia
17 genetic variants across 8 genes have been associated with Pathological Myopia in published research. Key genes include CERS3, EPHA1, MIPEP.
Associated variants17 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs2730260 | VIPR2 | GWAS association (p=9.0e-14) | Meta-analysis |
| rs7839488 | SNTB1 | GWAS association (p=2.0e-11) | Meta-analysis |
| rs547989689 | CERS3 | GWAS association (p=4.0e-17) | Major Consortium Study |
| rs575962315 | TMEM108 | GWAS association (p=1.0e-12) | Major Consortium Study |
| rs371244418 | OR51V1 | GWAS association (p=1.0e-12) | Major Consortium Study |
| rs1019688035 | — | GWAS association (p=3.0e-12) | Major Consortium Study |
| rs145413159 | — | GWAS association (p=6.0e-12) | Major Consortium Study |
| rs147917611 | — | GWAS association (p=9.0e-12) | Major Consortium Study |
| rs564955429 | EPHA1 | GWAS association (p=1.0e-11) | Major Consortium Study |
| rs549300642 | — | GWAS association (p=1.0e-11) | Major Consortium Study |
| rs149121136 | — | GWAS association (p=1.0e-11) | Major Consortium Study |
| rs368401784 | — | GWAS association (p=1.0e-11) | Major Consortium Study |
| rs573397921 | — | GWAS association (p=2.0e-11) | Major Consortium Study |
| rs9318086 | MIPEP | GWAS association (p=2.0e-16) | Large GWAS |
| rs373767 | — | GWAS association (p=3.0e-10) | Large GWAS |
| rs13382811 | ZEB2 | GWAS association (p=6.0e-10) | Large GWAS |
| rs6469937 | SNTB1 | GWAS association (p=2.0e-09) | Large GWAS |
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.