rs7928810

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GWAS Catalog Trait Associations (7)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

diastolic blood pressure

Koskeridis F et al. “Multi-trait association analysis reveals shared genetic loci between Alzheimer's disease and cardiovascular traits.” Nature Communications 15(1):9827 (2024)
Allele C
OR 0.01
p 2.0e-14
N 1,212,859
Large GWAS
European

body mass index, type 2 diabetes mellitus

Huang LO et al. “Genome-wide discovery of genetic loci that uncouple excess adiposity from its comorbidities.” Nature Metabolism 3(2):228-243 (2021)
Allele A
OR —
p 2.0e-12
N 449,443
Large GWAS
multi-ancestry

systolic blood pressure, body mass index

Huang LO et al. “Genome-wide discovery of genetic loci that uncouple excess adiposity from its comorbidities.” Nature Metabolism 3(2):228-243 (2021)
Allele A
OR —
p 9.0e-12
N 489,364
Large GWAS
multi-ancestry

pulse pressure measurement

Yang ML et al. “Sex-specific genetic architecture of blood pressure.” Nature Medicine 30(3):818-828 (2024)
Allele C
OR 0.02
p 1.0e-10
N 174,664
Large GWAS
multi-ancestry

diabetes mellitus

Schoeler T et al. “Participation bias in the UK Biobank distorts genetic associations and downstream analyses.” Nature Human Behaviour 7(7):1216-1227 (2023)
Allele C
OR 0.00
p 1.0e-9
N 283,227
Major Consortium StudyLarge GWAS
European

body mass index

Winkler TW et al. “The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.” Plos Genetics 11(10):e1005378 (2015)
Allele A
OR —
β 0.016
p 6.0e-9
N 309,889
Large GWAS
European

systolic blood pressure

Yang ML et al. “Sex-specific genetic architecture of blood pressure.” Nature Medicine 30(3):818-828 (2024)
Allele C
OR 0.02
p 2.0e-11
N 174,664
Large GWAS
multi-ancestry

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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