rs8078336
This is a regulatory region variant variant in the LRRC37A2 gene.
▶GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
pulse pressure measurement
Yang ML et al. “Sex-specific genetic architecture of blood pressure.” Nature Medicine 30(3):818-828 (2024)
Allele G
OR 0.06
p 3.0e-16
N 349,328
Large GWAS
multi-ancestry
systolic blood pressure
Yang ML et al. “Sex-specific genetic architecture of blood pressure.” Nature Medicine 30(3):818-828 (2024)
Allele G
OR 0.06
p 1.0e-13
N 349,328
Large GWAS
multi-ancestry
left atrium capacity
Pirruccello JP et al. “Deep learning of left atrial structure and function provides link to atrial fibrillation risk.” Nature Communications 15(1):4304 (2024)
Allele G
OR 0.14
p 3.0e-8
N 33,893
Large GWAS
About LRRC37A2
Predicted to enable ATP binding activity; ATP hydrolysis activity; and metal ion binding activity. Predicted to be involved in SNARE complex disassembly and protein transport. Predicted to be located in cytoplasm and membrane. [provided by Alliance of Genome Resources, Jul 2025]
View all LRRC37A2 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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