rs818022

This variant is located in the INO80D gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

hypothyroidism

Rand SA et al. “Genome-wide association study and polygenic risk prediction of hypothyroidism.” Nature Genetics 57(12):3007-3015 (2025)

Allele T

OR —

β 0.032

p 9.0e-9

N 1,178,661

Large GWAS

European

About INO80D

Involved in several processes, including chromatin remodeling; regulation of chromosome organization; and regulation of nucleobase-containing compound metabolic process. Part of Ino80 complex. [provided by Alliance of Genome Resources, Jul 2025]

View all INO80D variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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