rs838142
This is a upstream gene variant variant in the FUT1 gene.
▶GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
urinary albumin to creatinine ratio
Teumer A et al. “Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria.” Nature Communications 10(1):4130 (2019)
Allele A
OR 0.02
p 9.0e-14
N 547,361
Large GWAS
European
Casanova F et al. “A genome-wide association study implicates multiple mechanisms influencing raised urinary albumin-creatinine ratio.” Human Molecular Genetics 28(24):4197-4207 (2019)
Allele A
OR 0.02
p 1.0e-12
N 437,027
Large GWAS
European
albuminuria
Haas ME et al. “Genetic Association of Albuminuria with Cardiometabolic Disease and Blood Pressure.” American Journal of Human Genetics 103(4):461-473 (2018)
Allele A
OR 0.01
p 1.0e-9
N 302,687
Large GWAS
European
About FUT1
This gene encodes a Golgi stack membrane protein that is involved in the creation of a precursor of the H antigen, which is required for the final step in the synthesis of soluble A and B antigens. This is one of two genes encoding the galactoside 2-L-fucosyltransferase enzyme. Mutations in this gene are a cause of the H-Bombay blood group. [provided by RefSeq, Aug 2016]
View all FUT1 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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