rs860873
This variant is located in the CNN3 gene.
▶GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
fatty acid amount
Wu JH et al. “Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.” Circulation. Cardiovascular Genetics 6(2):171-83 (2013)
Allele A
OR 0.15
p 2.0e-14
N 8,961
Major Consortium StudyLarge GWAS
European
cigarettes per day measurement
Buchwald J et al. “Genome-wide association meta-analysis of nicotine metabolism and cigarette consumption measures in smokers of European descent.” Molecular Psychiatry 26(6):2212-2223 (2021)
Allele A
OR 0.11
p 4.0e-8
N 4,772
Meta-analysis
European
About CNN3
This gene encodes a protein with a markedly acidic C terminus; the basic N-terminus is highly homologous to the N-terminus of a related gene, CNN1. Members of the CNN gene family all contain similar tandemly repeated motifs. This encoded protein is associated with the cytoskeleton but is not involved in contraction. [provided by RefSeq, Jul 2008]
View all CNN3 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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