rs864882

This is a intron variant variant in the RABEPK gene.

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GWAS Catalog Trait Associations (2)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

cannabis dependence

Levey DF et al. “Multi-ancestry genome-wide association study of cannabis use disorder yields insight into disease biology and public health implications.” Nature Genetics 55(12):2094-2103 (2023)

Allele T

OR 0.02

p 3.0e-12

N 200,762

Large GWAS

European

substance-related disorder

Hatoum AS et al. “Multivariate genome-wide association meta-analysis of over 1 million subjects identifies loci underlying multiple substance use disorders.” Nature. Mental Health 1(3):210-223 (2023)

Allele C

OR —

β 0.015

p 3.0e-8

N 647,703

Meta-analysisLarge GWAS

European

About RABEPK

Predicted to be involved in receptor-mediated endocytosis and vesicle docking involved in exocytosis. Located in intracellular membrane-bounded organelle. [provided by Alliance of Genome Resources, Apr 2025]

View all RABEPK variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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