rs899428

This is a intron variant variant in the DOK2 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

body height

Fang H et al. “Harmonizing Genetic Ancestry and Self-identified Race/Ethnicity in Genome-wide Association Studies.” American Journal of Human Genetics 105(4):763-772 (2019)

Allele T

OR —

β 0.040

p 1.0e-8

N 345,563

Large GWAS

multi-ancestry

About DOK2

The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells. [provided by RefSeq, Jul 2008]

View all DOK2 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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