rs917793

This is a intron variant variant in the YKT6 gene.

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GWAS Catalog Trait Associations (2)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

metabolic syndrome

Ho CY et al. “A Genome-Wide Association Study of Metabolic Syndrome in the Taiwanese Population.” Nutrients 16(1) (2023)

Allele A

OR 0.09

p 4.0e-11

N 107,230

Large GWAS

East Asian

blood glucose amount

Nagy R et al. “Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.” Genome Medicine 9(1):23 (2017)

Allele T

OR 0.16

p 3.0e-24

N 29,900

Major Consortium StudyLarge GWAS

European

About YKT6

This gene product is one of the SNARE recognition molecules implicated in vesicular transport between secretory compartments. It is a membrane associated, isoprenylated protein that functions at the endoplasmic reticulum-Golgi transport step. This protein is highly conserved from yeast to human and can functionally complement the loss of the yeast homolog in the yeast secretory pathway. [provided by RefSeq, Jul 2008]

View all YKT6 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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