rs9291822

This is a intron variant variant in the CWC27 gene.

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GWAS Catalog Trait Associations (2)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

body mass index

Harris BHL et al. “New role of fat-free mass in cancer risk linked with genetic predisposition.” Scientific Reports 14(1):7270 (2024)

Allele T

OR 0.01

p 3.0e-9

N 342,566

Large GWAS

European

body height

Richardson TG et al. “Use of genetic variation to separate the effects of early and later life adiposity on disease risk: mendelian randomisation study.” Bmj (clinical Research Ed.) 369:m1203 (2020)

Allele C

OR 0.01

p 1.0e-8

N 453,169

Large GWAS

European

About CWC27

Predicted to enable peptidyl-prolyl cis-trans isomerase activity. Predicted to be involved in protein folding. Located in nucleoplasm. Part of U2-type precatalytic spliceosome and catalytic step 2 spliceosome. [provided by Alliance of Genome Resources, Jul 2025]

View all CWC27 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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