rs954244

GWAS Catalog Trait Associations (29)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

triglyceride measurement

Allele C
OR 0.02
p 8.0e-27
N 928,679
Large GWAS
multi-ancestry
Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele C
OR 0.02
p 2.0e-12
N 450,015
Large GWAS
multi-ancestry

high density lipoprotein cholesterol measurement

Allele C
OR 0.02
p 5.0e-21
N 928,679
Large GWAS
multi-ancestry
Sakaue S et al. A cross-population atlas of genetic associations for 220 human phenotypes. Nature Genetics 53(10):1415-1424 (2021)
Allele C
OR 0.01
p 3.0e-8
N 390,103
Large GWAS
multi-ancestry

triglycerides to phosphoglycerides ratio

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele G
OR 0.02
p 4.0e-15
N 450,015
Large GWAS
multi-ancestry

triglycerides to total lipids in small HDL percentage

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele G
OR 0.02
p 6.0e-15
N 450,015
Large GWAS
multi-ancestry

triglycerides in medium LDL measurement

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele G
OR 0.02
p 7.0e-14
N 450,015
Large GWAS
multi-ancestry

phospholipids in large VLDL measurement

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele G
OR 0.02
p 2.0e-13
N 450,015
Large GWAS
multi-ancestry

triglycerides in small HDL measurement

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele G
OR 0.02
p 2.0e-13
N 450,015
Large GWAS
multi-ancestry

concentration of very large VLDL particles measurement

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele G
OR 0.02
p 4.0e-13
N 450,015
Large GWAS
multi-ancestry

total lipids in very large VLDL measurement

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele G
OR 0.02
p 4.0e-13
N 450,015
Large GWAS
multi-ancestry

triglycerides in very large VLDL measurement

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele G
OR 0.02
p 5.0e-13
N 450,015
Large GWAS
multi-ancestry

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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