rs967645
This variant is located in the SARM1 gene.
▶GWAS Catalog Trait Associations (27)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (27)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
ras-related protein Rab-35 measurement
Allele T
OR 0.30
p 3.0e-35
N 3,301
Large GWAS
European
bone sialoprotein 2 measurement
Allele T
OR —
β 0.260
p 2.0e-26
N 3,301
Large GWAS
European
DCN1-like protein 5 measurement
Allele T
OR 0.25
p 8.0e-26
N 3,301
Large GWAS
European
apolipoprotein A-V measurement
Allele T
OR 0.25
p 5.0e-25
N 3,301
Large GWAS
European
cation-dependent mannose-6-phosphate receptor measurement
Allele T
OR 0.23
p 1.0e-20
N 3,301
Large GWAS
European
tRNA (guanine-N(7)-)-methyltransferase measurement
Pietzner M et al. “Mapping the proteo-genomic convergence of human diseases.” Science (new York, N.y.) 374(6569):eabj1541 (2021)
Allele T
OR 0.12
p 4.0e-19
N 10,708
Large GWAS
European
ephrin-B1 measurement
Allele T
OR 0.21
p 1.0e-18
N 3,301
Large GWAS
European
level of LysM and putative peptidoglycan-binding domain-containing protein 4 in blood serum
Kuliesius J et al. “Efficient candidate drug target discovery through proteogenomics in a Scottish cohort.” Communications Biology 8(1):1300 (2025)
Allele T
OR 0.72
p 6.0e-16
N 191
Small GWAS
European
Abelson tyrosine-protein kinase 2 measurement
Allele T
OR —
β 0.200
p 7.0e-16
N 3,301
Large GWAS
European
phospholipid level, high density lipoprotein cholesterol measurement
Richardson TG et al. “Characterising metabolomic signatures of lipid-modifying therapies through drug target mendelian randomisation.” Plos Biology 20(2):e3001547 (2022)
Allele C
OR 0.03
p 1.0e-14
N 115,082
Large GWAS
European
About SARM1
Enables NAD+ nucleosidase activity; NAD+ nucleosidase activity, cyclic ADP-ribose generating; and identical protein binding activity. Involved in NAD catabolic process and response to axon injury. Is active in mitochondrion. [provided by Alliance of Genome Resources, Apr 2025]
View all SARM1 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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