rs972600
This variant is located in the MIOS gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
Alzheimer disease
Chung J et al. “Genome-wide association and multi-omics studies identify MGMT as a novel risk gene for Alzheimer's disease among women.” Alzheimer's & Dementia : the Journal of the Alzheimer's Association 19(3):896-908 (2023)
Allele G
OR 2.72
p 3.0e-9
N 31
Small GWAS
European
About MIOS
Predicted to enable zinc ion binding activity. Involved in cellular response to amino acid starvation; positive regulation of TORC1 signaling; and protein-containing complex localization. Located in several cellular components, including cytosol; lysosomal membrane; and nucleoplasm. Part of GATOR2 complex. [provided by Alliance of Genome Resources, Jul 2025]
View all MIOS variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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