rs977987

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GWAS Catalog Trait Associations (3)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

aortic stenosis

Kany S et al. “Multitrait analyses identify genetic variants associated with aortic valve function and aortic stenosis risk.” Nature Genetics 58(1):47-56 (2026)

Allele G

OR 0.04

p 3.0e-20

N 1,984,229

Large GWAS

European

Dupuytren Contracture

Ng M et al. “A Genome-wide Association Study of Dupuytren Disease Reveals 17 Additional Variants Implicated in Fibrosis.” American Journal of Human Genetics 101(3):417-427 (2017)

Allele G

OR 1.15

p 5.0e-10

N 8,557

Large GWAS

multi-ancestry

diverticular disease

Wu Y et al. “150 risk variants for diverticular disease of intestine prioritize cell types and enable polygenic prediction of disease susceptibility.” Cell Genomics 3(7):100326 (2023)

Allele G

OR 0.03

p 6.0e-9

N 454,768

Large GWAS

European

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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