rs9808800

This is a intron variant variant in the DSCAM gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

age of onset of Alzheimer disease

Li YJ et al. “Identification of novel genes for age-at-onset of Alzheimer's disease by combining quantitative and survival trait analyses.” Alzheimer's & Dementia : the Journal of the Alzheimer's Association 19(7):3148-3157 (2023)

Allele A

OR 1.06

p 5.0e-9

N 19,564

Large GWAS

European

About DSCAM

This gene is a member of the immunoglobulin superfamily of cell adhesion molecules (Ig-CAMs), and is involved in human central and peripheral nervous system development. This gene is a candidate for Down syndrome and congenital heart disease (DSCHD). A gene encoding a similar Ig-CAM protein is located on chromosome 11. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2012]

View all DSCAM variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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