rs986391
▶GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
smoking behavior trait
Wootton RE et al. “Evidence for causal effects of lifetime smoking on risk for depression and schizophrenia: a Mendelian randomisation study.” Psychological Medicine 50(14):2435-2443 (2020)
Allele G
OR 0.02
p 9.0e-15
N 462,690
Large GWAS
European
substance-related disorder
Lai D et al. “Genome-wide meta-analyses of cross substance use disorders in diverse populations.” Molecular Psychiatry 31(3):1619-1633 (2026)
Allele A
OR 6.52
p 7.0e-11
N 1,517,369
Large GWAS
multi-ancestry
health study participation
Tyrrell J et al. “Genetic predictors of participation in optional components of UK Biobank.” Nature Communications 12(1):886 (2021)
Allele G
OR 0.97
p 7.0e-9
N 294,787
Major Consortium StudyLarge GWAS
European
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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