rs9940555
This is a intron variant variant in the NSMCE1 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
peripheral arterial disease, traffic air pollution measurement
Ward-Caviness CK et al. “Genetic Variants in the Bone Morphogenic Protein Gene Family Modify the Association between Residential Exposure to Traffic and Peripheral Arterial Disease.” Plos One 11(4):e0152670 (2016)
Allele G
OR 7.72
p 4.0e-8
N 2,177
Large GWAS
multi-ancestry
About NSMCE1
Enables protein dimerization activity and ubiquitin protein ligase activity. Involved in DNA damage response. Located in nucleoplasm. Part of Smc5-Smc6 complex. [provided by Alliance of Genome Resources, Jul 2025]
View all NSMCE1 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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