rs9958628
This is a intron variant variant in the ARHGAP28 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
asparaginase hypersensitivity
Liu Y et al. “Class II Human Leukocyte Antigen Variants Associate With Risk of Pegaspargase Hypersensitivity.” Clinical Pharmacology and Therapeutics 110(3):794-802 (2021)
Allele T
OR 3.69
p 9.0e-9
N 1,607
Large GWAS
multi-ancestry
About ARHGAP28
Predicted to enable GTPase activator activity. Predicted to be involved in negative regulation of stress fiber assembly; regulation of actin filament polymerization; and regulation of small GTPase mediated signal transduction. Located in cell junction and nucleoplasm. Implicated in allergic disease. Biomarker of meningioma. [provided by Alliance of Genome Resources, Jul 2025]
View all ARHGAP28 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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