Trait
SNPs associated with Alcoholic liver disease
8 genetic variants across 4 genes have been associated with Alcoholic liver disease in published research. Key genes include ADH1B, HFE, PNPLA3.
Associated variants8 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs1799945 | HFE | Increased risk of alcoholic liver disease | Meta-analysis |
| rs738409 | PNPLA3 | GWAS association (p=3.0e-121) | Major Consortium Study |
| rs3747207 | PNPLA3 | GWAS association (p=3.0e-101) | Major Consortium Study |
| rs2294915 | — | GWAS association (p=4.0e-17) | Major Consortium Study |
| rs2066702 | ADH1B | GWAS association (p=4.0e-13) | Major Consortium Study |
| rs13119654 | — | GWAS association (p=3.0e-11) | Major Consortium Study |
| rs58542926 | TM6SF2 | GWAS association (p=2.0e-17) | Major Consortium Study |
| rs1229984 | ADH1B | GWAS association (p=3.0e-48) | Major Consortium Study |
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.