rs2294915
▶GWAS Catalog Trait Associations (24)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (24)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
alcoholic liver cirrhosis
Schwantes-An TH et al. “Genome-wide Association Study and Meta-analysis on Alcohol-Associated Liver Cirrhosis Identifies Genetic Risk Factors.” Hepatology (baltimore, Md.) 73(5):1920-1931 (2021)
Allele T
OR 0.74
p 1.0e-58
N 1,977
Meta-analysis
European
urate measurement
Cho C et al. “Large-scale cross-ancestry genome-wide meta-analysis of serum urate.” Nature Communications 15(1):3441 (2024)
Allele T
OR 0.03
p 3.0e-29
N 1,029,323
Meta-analysisLarge GWAS
multi-ancestry
abnormality of serum enzyme levels
Verma A et al. “Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.” Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele C
OR 0.24
p 6.0e-27
N 437,561
Major Consortium StudyLarge GWAS
European
hepatocellular carcinoma
Buch S et al. “Genetic variation in TERT modifies the risk of hepatocellular carcinoma in alcohol-related cirrhosis: results from a genome-wide case-control study.” Gut 72(2):381-391 (2023)
Allele T
OR 1.75
p 2.0e-19
N 1,910
Large GWAS
European
Sato G et al. “Pan-cancer and cross-population genome-wide association studies dissect shared genetic backgrounds underlying carcinogenesis.” Nature Communications 14(1):3671 (2023)
Allele T
OR 1.90
p 2.0e-11
N 334,682
Large GWAS
European
triglyceride measurement
Verma A et al. “Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.” Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele C
OR 0.03
p 3.0e-17
N 391,626
Major Consortium StudyLarge GWAS
European
Harshfield EL et al. “Genome-wide analysis of blood lipid metabolites in over 5000 South Asians reveals biological insights at cardiometabolic disease loci.” Bmc Medicine 19(1):232 (2021)
Allele C
OR 0.08
p 4.0e-13
N 5,662
Large GWAS
South Asian
alcoholic liver disease
Verma A et al. “Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.” Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele C
OR 0.30
p 4.0e-17
N 58,946
Major Consortium StudyLarge GWAS
Hispanic or Latin American
drug use measurement, gout
Verma A et al. “Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.” Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele C
OR 0.10
p 4.0e-17
N 404,034
Major Consortium StudyLarge GWAS
multi-ancestry
level of glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic in blood
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele T
OR 0.05
p 4.0e-15
N 47,745
Large GWAS
European
beta-Ala-His dipeptidase measurement
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele T
OR 0.05
p 3.0e-14
N 47,745
Large GWAS
European
interleukin-1 receptor accessory protein measurement
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele T
OR 0.03
p 1.0e-13
N 47,745
Large GWAS
European
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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