Trait
SNPs associated with complement C3 measurement
20 genetic variants across 8 genes have been associated with complement C3 measurement in published research. Key genes include C2, C3, CFH.
Associated variants20 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs11672613 | C3 | GWAS association (p=6.0e-123) | Large GWAS |
| rs11569466 | C3 | GWAS association (p=2.0e-58) | Large GWAS |
| rs3753396 | CFH | GWAS association (p=2.0e-38) | Large GWAS |
| rs72734328 | CFH | GWAS association (p=4.0e-34) | Large GWAS |
| rs1047286 | C3 | GWAS association (p=7.0e-34) | Large GWAS |
| rs12975366 | LILRB5 | GWAS association (p=7.0e-24) | Large GWAS |
| rs556679 | C2 | GWAS association (p=2.0e-23) | Large GWAS |
| rs114492815 | — | GWAS association (p=2.0e-23) | Large GWAS |
| rs529825 | CFH | GWAS association (p=1.0e-17) | Large GWAS |
| rs112635299 | — | GWAS association (p=1.0e-17) | Large GWAS |
| rs1260326 | GCKR | GWAS association (p=2.0e-17) | Large GWAS |
| rs11569479 | C3 | GWAS association (p=6.0e-17) | Large GWAS |
| rs1800562 | HFE | GWAS association (p=2.0e-16) | Large GWAS |
| rs4657825 | — | GWAS association (p=1.0e-14) | Large GWAS |
| rs12949906 | FAM117A | GWAS association (p=3.0e-12) | Large GWAS |
| rs3753394 | CFH | GWAS association (p=7.0e-11) | Large GWAS |
| rs10414623 | C3 | GWAS association (p=1.0e-10) | Large GWAS |
| rs3745567 | C3 | GWAS association (p=2.0e-09) | Large GWAS |
| rs11569470 | C3 | GWAS association (p=1.0e-08) | Large GWAS |
| rs844 | FCGR2B | GWAS association (p=1.0e-08) | Large GWAS |
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.