Trait
SNPs associated with Genetic chronic primary adrenal insufficiency
10 genetic variants across 7 genes have been associated with Genetic chronic primary adrenal insufficiency in published research. Key genes include AIRE, ATXN2, BACH2.
Associated variants10 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs3998178 | HLA-DQA1 | GWAS association (p=4.0e-179) | Large GWAS |
| rs10806425 | BACH2 | GWAS association (p=3.0e-27) | Large GWAS |
| rs74203920 | AIRE | GWAS association (p=9.0e-25) | Large GWAS |
| rs2476601 | PTPN22 | GWAS association (p=6.0e-17) | Large GWAS |
| rs2075876 | AIRE | GWAS association (p=8.0e-14) | Large GWAS |
| rs1464510 | LPP | GWAS association (p=7.0e-12) | Large GWAS |
| rs11571303 | — | GWAS association (p=5.0e-11) | Large GWAS |
| rs11203203 | UBASH3A | GWAS association (p=9.0e-10) | Large GWAS |
| rs8112143 | — | GWAS association (p=1.0e-08) | Large GWAS |
| rs7137828 | ATXN2 | GWAS association (p=5.0e-08) | Large GWAS |
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.