Trait
SNPs associated with Heart Valve Disease
12 genetic variants across 4 genes have been associated with Heart Valve Disease in published research. Key genes include FADS2, LPA, P2RX3.
Associated variants12 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs10455872 | LPA | GWAS association (p=2.0e-66) | Major Consortium Study |
| rs6702619 | — | GWAS association (p=5.0e-30) | Major Consortium Study |
| rs1852687 | — | GWAS association (p=6.0e-19) | Major Consortium Study |
| rs117202424 | — | GWAS association (p=3.0e-18) | Major Consortium Study |
| rs2421649 | — | GWAS association (p=3.0e-15) | Major Consortium Study |
| rs174564 | FADS2 | GWAS association (p=9.0e-14) | Major Consortium Study |
| rs583104 | — | GWAS association (p=2.0e-13) | Major Consortium Study |
| rs7804293 | — | GWAS association (p=8.0e-13) | Major Consortium Study |
| rs6982502 | — | GWAS association (p=4.0e-12) | Major Consortium Study |
| rs4970836 | PSRC1 | GWAS association (p=4.0e-12) | Major Consortium Study |
| rs10024267 | — | GWAS association (p=5.0e-22) | Large GWAS |
| rs200854727 | P2RX3 | GWAS association (p=2.0e-08) | Large GWAS |
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.