Trait
SNPs associated with Hypermetropia
29 genetic variants across 11 genes have been associated with Hypermetropia in published research. Key genes include BICC1, C14orf39, CD55.
Associated variants29 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs524952 | — | GWAS association (p=4.0e-32) | Major Consortium Study |
| rs7744813 | KCNQ5 | GWAS association (p=4.0e-31) | Major Consortium Study |
| rs12193446 | LAMA2 | GWAS association (p=3.0e-29) | Major Consortium Study |
| rs3138142 | RDH5 | GWAS association (p=8.0e-28) | Major Consortium Study |
| rs634990 | — | GWAS association (p=2.0e-26) | Major Consortium Study |
| rs7188859 | — | GWAS association (p=3.0e-26) | Major Consortium Study |
| rs3138141 | RDH5 | GWAS association (p=2.0e-23) | Major Consortium Study |
| rs11602008 | — | GWAS association (p=3.0e-17) | Major Consortium Study |
| rs11606250 | — | GWAS association (p=8.0e-17) | Major Consortium Study |
| rs178597 | — | GWAS association (p=9.0e-17) | Major Consortium Study |
| rs2093210 | C14orf39 | GWAS association (p=3.0e-16) | Major Consortium Study |
| rs58004513 | SLC14A2 | GWAS association (p=2.0e-15) | Major Consortium Study |
| rs724154 | — | GWAS association (p=4.0e-15) | Major Consortium Study |
| rs10089517 | — | GWAS association (p=8.0e-15) | Major Consortium Study |
| rs11594240 | BICC1 | GWAS association (p=2.0e-13) | Major Consortium Study |
| rs1550094 | PRSS56 | GWAS association (p=2.0e-13) | Major Consortium Study |
| rs869422 | — | GWAS association (p=2.0e-13) | Major Consortium Study |
| rs12191766 | — | GWAS association (p=7.0e-13) | Major Consortium Study |
| rs2661358 | CD55 | GWAS association (p=9.0e-13) | Major Consortium Study |
| rs2908972 | — | GWAS association (p=3.0e-12) | Major Consortium Study |
| rs5442 | GNB3 | GWAS association (p=3.0e-12) | Major Consortium Study |
| rs11200633 | LOC105378525 | GWAS association (p=5.0e-12) | Major Consortium Study |
| rs4794029 | — | GWAS association (p=7.0e-12) | Major Consortium Study |
| rs58795 | — | GWAS association (p=1.0e-11) | Major Consortium Study |
| rs8075811 | — | GWAS association (p=2.0e-11) | Major Consortium Study |
| rs56218609 | LOC124905590 | GWAS association (p=3.0e-11) | Major Consortium Study |
| rs72621438 | — | GWAS association (p=3.0e-11) | Major Consortium Study |
| rs1340044 | — | GWAS association (p=1.0e-14) | Major Consortium Study |
| rs71640857 | — | GWAS association (p=5.0e-15) | Major Consortium Study |
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.