Trait
SNPs associated with Hyperthyroidism
59 genetic variants across 15 genes have been associated with Hyperthyroidism in published research. Key genes include CTLA4, FGF7, HLA-DPA1.
Associated variants59 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs7747236 | — | GWAS association (p=8.0e-117) | Large GWAS |
| rs12148331 | — | GWAS association (p=2.0e-66) | Large GWAS |
| rs1794280 | — | GWAS association (p=2.0e-44) | Large GWAS |
| rs2160215 | TSHR | GWAS association (p=2.0e-37) | Large GWAS |
| rs2300519 | TSHR | GWAS association (p=8.0e-34) | Large GWAS |
| rs28687418 | — | GWAS association (p=5.0e-32) | Large GWAS |
| rs41269265 | ZNF184 | GWAS association (p=8.0e-32) | Large GWAS |
| rs58722186 | LOC105371356 | GWAS association (p=7.0e-30) | Large GWAS |
| rs28366272 | — | GWAS association (p=6.0e-29) | Large GWAS |
| rs6754506 | — | GWAS association (p=3.0e-28) | Large GWAS |
| rs3087243 | CTLA4 | GWAS association (p=1.0e-22) | Large GWAS |
| rs11571297 | — | GWAS association (p=2.0e-22) | Large GWAS |
| rs2046045 | PDE8B | GWAS association (p=4.0e-22) | Large GWAS |
| rs1033701 | — | GWAS association (p=2.0e-21) | Large GWAS |
| rs2476601 | PTPN22 | GWAS association (p=6.0e-21) | Large GWAS |
| rs714862 | — | GWAS association (p=4.0e-20) | Large GWAS |
| rs334706 | NFIA | GWAS association (p=1.0e-18) | Large GWAS |
| rs147828653 | — | GWAS association (p=6.0e-18) | Large GWAS |
| rs7873463 | — | GWAS association (p=4.0e-17) | Large GWAS |
| rs12515498 | — | GWAS association (p=6.0e-17) | Large GWAS |
| rs6679677 | PHTF1 | GWAS association (p=6.0e-17) | Large GWAS |
| rs2215981 | TSHR | GWAS association (p=3.0e-16) | Large GWAS |
| rs34038921 | — | GWAS association (p=3.0e-16) | Large GWAS |
| rs3118358 | — | GWAS association (p=1.0e-15) | Large GWAS |
| rs3135293 | TRIM27 | GWAS association (p=1.0e-13) | Large GWAS |
| rs11865979 | — | GWAS association (p=2.0e-13) | Large GWAS |
| rs1042131 | HLA-DPA1 | GWAS association (p=5.0e-13) | Large GWAS |
| rs17477923 | — | GWAS association (p=6.0e-13) | Large GWAS |
| rs56983610 | LOC105376817 | GWAS association (p=7.0e-13) | Large GWAS |
| rs118039499 | — | GWAS association (p=2.0e-12) | Large GWAS |
| rs4338740 | FGF7 | GWAS association (p=3.0e-12) | Large GWAS |
| rs73575083 | LOC105371356 | GWAS association (p=4.0e-12) | Large GWAS |
| rs2125747 | — | GWAS association (p=2.0e-11) | Large GWAS |
| rs11038357 | — | GWAS association (p=3.0e-11) | Large GWAS |
| rs6757890 | — | GWAS association (p=4.0e-11) | Large GWAS |
| rs12592277 | — | GWAS association (p=3.0e-10) | Large GWAS |
| rs385863 | LOC105378120 | GWAS association (p=4.0e-10) | Large GWAS |
| rs8077245 | — | GWAS association (p=5.0e-10) | Large GWAS |
| rs2983514 | — | GWAS association (p=5.0e-10) | Large GWAS |
| rs12138950 | LOC105376817 | GWAS association (p=6.0e-10) | Large GWAS |
| rs6754292 | — | GWAS association (p=8.0e-10) | Large GWAS |
| rs13098877 | — | GWAS association (p=9.0e-10) | Large GWAS |
| rs1863144 | — | GWAS association (p=2.0e-09) | Large GWAS |
| rs334702 | — | GWAS association (p=2.0e-09) | Large GWAS |
| rs4733823 | — | GWAS association (p=2.0e-09) | Large GWAS |
| rs140851213 | — | GWAS association (p=5.0e-09) | Large GWAS |
| rs3117138 | TSBP1 | GWAS association (p=5.0e-09) | Large GWAS |
| rs7555082 | — | GWAS association (p=7.0e-09) | Large GWAS |
| rs925488 | — | GWAS association (p=1.0e-08) | Large GWAS |
| rs2476491 | — | GWAS association (p=1.0e-08) | Large GWAS |
| rs3758723 | — | GWAS association (p=1.0e-08) | Large GWAS |
| rs6908626 | — | GWAS association (p=2.0e-08) | Large GWAS |
| rs8043085 | — | GWAS association (p=2.0e-08) | Large GWAS |
| rs604912 | — | GWAS association (p=3.0e-08) | Large GWAS |
| rs66760320 | — | GWAS association (p=4.0e-08) | Large GWAS |
| rs78254323 | — | GWAS association (p=4.0e-08) | Large GWAS |
| rs1169151 | — | GWAS association (p=4.0e-08) | Large GWAS |
| rs6131010 | — | GWAS association (p=4.0e-08) | Large GWAS |
| rs143210911 | PRLR | GWAS association (p=5.0e-08) | Large GWAS |
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.