Trait
SNPs associated with Juvenile idiopathic arthritis
16 genetic variants across 7 genes have been associated with Juvenile idiopathic arthritis in published research. Key genes include AHI1, ATXN2, HLA-DQB1.
Associated variants16 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs2476601 | PTPN22 | Increased juvenile idiopathic arthritis risk | Meta-analysis |
| rs6679677 | PHTF1 | GWAS association (p=7.0e-30) | Large GWAS |
| rs11889341 | STAT4 | GWAS association (p=2.0e-19) | Large GWAS |
| rs953387 | — | GWAS association (p=3.0e-14) | Large GWAS |
| rs9960807 | — | GWAS association (p=3.0e-14) | Large GWAS |
| rs4766578 | ATXN2 | GWAS association (p=2.0e-13) | Large GWAS |
| rs2481065 | — | GWAS association (p=4.0e-13) | Large GWAS |
| rs706778 | IL2RA | GWAS association (p=1.0e-12) | Large GWAS |
| rs2614258 | AHI1 | GWAS association (p=9.0e-12) | Large GWAS |
| rs79815064 | — | GWAS association (p=3.0e-11) | Large GWAS |
| rs6434390 | — | GWAS association (p=1.0e-09) | Large GWAS |
| rs7647909 | — | GWAS association (p=2.0e-09) | Large GWAS |
| rs12430303 | — | GWAS association (p=2.0e-09) | Large GWAS |
| rs4713573 | HLA-DQB1 | GWAS association (p=3.0e-09) | Large GWAS |
| rs4869314 | — | GWAS association (p=3.0e-09) | Large GWAS |
| rs1051533 | — | GWAS association (p=1.0e-08) | Large GWAS |
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.