Trait
SNPs associated with Late-Onset Myasthenia Gravis
9 genetic variants across 4 genes have been associated with Late-Onset Myasthenia Gravis in published research. Key genes include CHRNA1, CTLA4, PTPN22.
Associated variants9 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs2476601 | PTPN22 | GWAS association (p=5.0e-27) | Meta-analysis |
| rs7239261 | TNFRSF11A | GWAS association (p=2.0e-12) | Meta-analysis |
| rs72848204 | — | GWAS association (p=1.0e-11) | Meta-analysis |
| rs231779 | CTLA4 | GWAS association (p=5.0e-09) | Meta-analysis |
| rs9271375 | — | GWAS association (p=2.0e-19) | Large GWAS |
| rs4369774 | — | GWAS association (p=6.0e-19) | Large GWAS |
| rs111945767 | — | GWAS association (p=3.0e-17) | Large GWAS |
| rs35274388 | CHRNA1 | GWAS association (p=1.0e-12) | Large GWAS |
| rs6998967 | — | GWAS association (p=9.0e-10) | Large GWAS |
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.