Trait
SNPs associated with Thyrotoxicosis
14 genetic variants across 9 genes have been associated with Thyrotoxicosis in published research. Key genes include CTLA4, HLA-DQA1, LOC105371356.
Associated variants14 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs10799824 | LOC105376817 | GWAS association (p=2.0e-29) | Major Consortium Study |
| rs6885099 | PDE8B | GWAS association (p=1.0e-23) | Major Consortium Study |
| rs73575085 | LOC105371356 | GWAS association (p=8.0e-23) | Major Consortium Study |
| rs58266067 | — | GWAS association (p=2.0e-21) | Major Consortium Study |
| rs334706 | NFIA | GWAS association (p=6.0e-19) | Major Consortium Study |
| rs753760 | PDE10A | GWAS association (p=2.0e-14) | Major Consortium Study |
| rs10223666 | POLR1C | GWAS association (p=3.0e-14) | Major Consortium Study |
| rs7825175 | NRG1 | GWAS association (p=3.0e-14) | Major Consortium Study |
| rs3758723 | — | GWAS association (p=2.0e-13) | Major Consortium Study |
| rs13020935 | — | GWAS association (p=3.0e-12) | Major Consortium Study |
| rs3087243 | CTLA4 | GWAS association (p=3.0e-18) | Major Consortium Study |
| rs73398264 | — | GWAS association (p=2.0e-18) | Major Consortium Study |
| rs78775620 | — | GWAS association (p=6.0e-20) | Major Consortium Study |
| rs9272445 | HLA-DQA1 | GWAS association (p=6.0e-27) | Major Consortium Study |
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.