ADAD1
adenosine deaminase domain containing 1
Summary
Predicted to enable double-stranded RNA adenosine deaminase activity; double-stranded RNA binding activity; and tRNA-specific adenosine deaminase activity. Predicted to be involved in RNA processing and adenosine to inosine editing. Predicted to act upstream of or within spermatid development. Predicted to be located in male germ cell nucleus. Predicted to be active in cytoplasm and nucleolus. [provided by Alliance of Genome Resources, Apr 2025]
Known Variants23 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs139643444 | 4:123,301,250 | A/G | — | uncertain significance |
| rs569397386 | 4:123,301,313 | C/A | — | uncertain significance |
| rs1794820432 | 4:123,301,343 | C/T | — | uncertain significance |
| rs146584990 | 4:123,302,249 | G/A | — | uncertain significance |
| rs200548828 | 4:123,302,329 | A/G | — | uncertain significance |
| rs778805626 | 4:123,314,747 | C/G | — | uncertain significance |
| rs1561538203 | 4:123,317,407 | A/G | — | uncertain significance |
| rs763527708 | 4:123,317,433 | A/G | — | uncertain significance |
| rs533027008 | 4:123,317,445 | G/A | — | uncertain significance |
| rs17388568 | 4:123,329,362 | G/A | intron variant | — |
| rs1329756668 | 4:123,332,424 | T/C | — | uncertain significance |
| rs2484665224 | 4:123,332,460 | C/G | — | uncertain significance |
| rs2484670797 | 4:123,333,769 | G/A | — | uncertain significance |
| rs912289238 | 4:123,333,793 | G/A | — | uncertain significance |
| rs553837648 | 4:123,333,923 | G/A | — | uncertain significance |
| rs772070988 | 4:123,336,647 | A/G | — | uncertain significance |
| rs55896948 | 4:123,342,114 | T/A | — | — |
| rs751689720 | 4:123,342,450 | C/T | — | uncertain significance |
| rs778239614 | 4:123,342,478 | G/A | — | uncertain significance |
| rs74845071 | 4:123,345,209 | T/G | intron variant | — |
| rs11732095 | 4:123,348,345 | A/G | intron variant | — |
| rs367937775 | 4:123,350,827 | A/G | — | uncertain significance |
| rs369500195 | 4:123,350,890 | T/A | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.