CNOT4
CCR4-NOT transcription complex subunit 4
Summary
The protein encoded by this gene is a subunit of the CCR4-NOT complex, a global transcriptional regulator. The encoded protein interacts with CNOT1 and has E3 ubiquitin ligase activity. Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jul 2010]
Known Variants22 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs1794717856 | 7:135,047,716 | G/T | — | uncertain significance |
| rs367826789 | 7:135,047,740 | G/A | — | uncertain significance |
| rs1340647021 | 7:135,047,774 | C/T | — | uncertain significance |
| rs759859047 | 7:135,047,834 | C/G | — | uncertain significance |
| rs754731577 | 7:135,047,905 | G/C | — | uncertain significance |
| rs1379999094 | 7:135,048,657 | T/C | — | uncertain significance |
| rs11772832 | 7:135,073,047 | T/C | intron variant | — |
| rs372237832 | 7:135,078,777 | C/G | — | uncertain significance |
| rs1796545780 | 7:135,078,828 | C/T | — | uncertain significance |
| rs376653608 | 7:135,078,964 | T/C | — | uncertain significance |
| rs368949226 | 7:135,078,991 | G/C | — | uncertain significance |
| rs376949221 | 7:135,079,012 | G/C | — | uncertain significance |
| rs564908475 | 7:135,080,547 | C/T | — | uncertain significance |
| rs1796646857 | 7:135,080,559 | T/C | — | uncertain significance |
| rs763386068 | 7:135,080,699 | A/G | — | — |
| rs3812281 | 7:135,082,751 | T/A | — | — |
| rs2718167 | 7:135,093,445 | C/T | intron variant | — |
| rs199552823 | 7:135,095,319 | G/A | — | uncertain significance |
| rs2551778 | 7:135,099,649 | C/T | regulatory region variant | — |
| rs17480616 | 7:135,123,060 | G/A | missense variant | — |
| rs2551769 | 7:135,138,331 | G/A | intron variant | — |
| rs10214966 | 7:135,196,642 | A/G | upstream gene variant | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.