ERI1

exoribonuclease 1

Summary

Enables 3'-5' exonuclease activity. Involved in maturation of 5.8S rRNA. Located in cytoplasm and nucleolus. [provided by Alliance of Genome Resources, Jul 2025]

Known Variants70 total

rsidPosition (GRCh37)AllelesClassClinVar
rs9181212588:8,860,583C/T—uncertain significance
rs10367667468:8,860,595G/C—likely benign
rs10487660118:8,860,601G/T—uncertain significance
rs7688297698:8,860,611C/A—uncertain significance
rs22886728:8,860,620T/C—benign
rs12098749548:8,860,622G/T—uncertain significance
rs24861750668:8,860,623C/A—uncertain significance
rs24861751528:8,860,635C/A—likely pathogenic
rs617367698:8,860,644C/G—likely benign
rs9794725798:8,860,678C/G—likely benign
rs69875588:8,862,521G/A——
rs69932448:8,863,059C/T——
rs2011662618:8,865,471T/G—likely benign
rs3744370308:8,865,490A/C—uncertain significance
rs1501862588:8,865,537T/C—uncertain significance
rs7717022188:8,865,544C/A—uncertain significance
rs7575141028:8,865,561C/T—uncertain significance
rs7504654848:8,865,562C/A—uncertain significance
rs2016434758:8,865,586C/T—uncertain significance
rs3776789418:8,865,636T/G—uncertain significance
rs7630276848:8,869,091T/C—likely benign
rs2012518578:8,869,092T/C—uncertain significance
rs14079383218:8,869,093A/G—uncertain significance
rs24862188918:8,869,116A/T—likely pathogenic
rs7515150298:8,869,162T/C—uncertain significance
rs24862194818:8,869,165A/G—likely pathogenic
rs1432206568:8,869,181T/C—likely benign
rs7558017668:8,869,197C/T—uncertain significance
rs96506168:8,869,199T/A—likely benign
rs24862199408:8,869,214A/T—likely pathogenic
rs9829117298:8,869,228C/T—likely pathogenic
rs29792568:8,871,710C/Tregulatory region variant—
rs5555197348:8,873,834A/G—likely benign
rs24862436118:8,873,847C/T—likely pathogenic
rs12433394348:8,873,849G/C—uncertain significance
rs1394842488:8,873,888C/T—likely benign
rs12211412568:8,873,916G/A—pathogenic
rs1132458838:8,873,925C/T—likely benign
rs7475932268:8,875,798T/C—likely benign
rs7517970768:8,875,826A/T—uncertain significance
rs18175193458:8,875,837C/G—uncertain significance
rs1498503008:8,875,885A/G—uncertain significance
rs7747498258:8,877,878G/C—uncertain significance
rs7762333818:8,877,881C/G—uncertain significance
rs7666250848:8,877,897C/T—likely pathogenic
rs12895833908:8,877,955C/T—uncertain significance
rs7500920998:8,887,309G/A—uncertain significance
rs24863086098:8,887,316A/C—uncertain significance
rs1397625748:8,887,350A/G—uncertain significance
rs3756904238:8,887,359G/A—uncertain significance
rs24863090368:8,887,363G/A—uncertain significance
rs349112868:8,887,367G/C—benign
rs14332809538:8,887,387A/C—pathogenic
rs24863092308:8,887,389T/C—likely pathogenic
rs7817179518:8,887,404C/G—uncertain significance
rs14292689018:8,887,420T/G—uncertain significance
rs14219069418:8,887,444G/A—uncertain significance
rs1466139458:8,887,457A/C—uncertain significance
rs3707166568:8,887,480G/A—uncertain significance
rs1412879118:8,887,492C/A—uncertain significance
rs10455298:8,890,098C/T3 prime UTR variant—
rs342517838:8,891,376T/Cdownstream gene variant—
rs117870268:8,902,371A/Tupstream gene variant—
rs45373058:8,902,670A/T——
rs69963748:8,907,951A/G——
rs29213788:8,914,812C/Gregulatory region variant—
rs30214168:8,919,136G/Aregulatory region variant—
rs48410938:8,920,269C/Gcoding sequence variant—
rs78466448:8,929,130A/T——
rs78291138:8,929,133C/Tdownstream gene variant—

Gene information from NCBI Gene. Variant classifications from ClinVar.