FOXO1
forkhead box O1
Summary
This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in myogenic growth and differentiation. Translocation of this gene with PAX3 has been associated with alveolar rhabdomyosarcoma. [provided by RefSeq, Jul 2008]
Known Variants68 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs17592236 | 13:41,131,932 | C/T | 3 prime UTR variant | benign |
| rs752155939 | 13:41,133,750 | A/T | — | uncertain significance |
| rs750150806 | 13:41,133,847 | T/C | — | uncertain significance |
| rs767915535 | 13:41,133,871 | C/T | — | uncertain significance |
| rs2137821490 | 13:41,133,920 | T/C | — | uncertain significance |
| rs890236166 | 13:41,134,004 | T/C | — | likely benign |
| rs1873915781 | 13:41,134,049 | G/A | — | uncertain significance |
| rs202038357 | 13:41,134,054 | G/C | — | uncertain significance |
| rs760979256 | 13:41,134,091 | G/A | — | uncertain significance |
| rs927500436 | 13:41,134,111 | G/A | — | uncertain significance |
| rs34650827 | 13:41,134,122 | C/T | — | benign |
| rs144907712 | 13:41,134,142 | C/T | — | uncertain significance |
| rs374723626 | 13:41,134,160 | G/A | — | uncertain significance |
| rs757179771 | 13:41,134,214 | G/A | — | uncertain significance |
| rs571854966 | 13:41,134,270 | C/T | — | likely benign |
| rs2501062625 | 13:41,134,282 | T/C | — | uncertain significance |
| rs1873947804 | 13:41,134,447 | G/A | — | uncertain significance |
| rs750700983 | 13:41,134,531 | C/T | — | uncertain significance |
| rs900224788 | 13:41,134,532 | T/C | — | uncertain significance |
| rs754164404 | 13:41,134,562 | C/T | — | uncertain significance |
| rs139436481 | 13:41,134,629 | A/G | — | likely benign |
| rs762850409 | 13:41,134,663 | C/G | — | uncertain significance |
| rs45624735 | 13:41,134,707 | A/G | — | benign |
| rs1199232111 | 13:41,134,864 | G/A | — | uncertain significance |
| rs3751436 | 13:41,135,038 | T/G | — | — |
| rs2755209 | 13:41,137,804 | A/G | — | — |
| rs2721068 | 13:41,139,712 | T/G | — | — |
| rs17446614 | 13:41,139,877 | G/A | intron variant | — |
| rs60250748 | 13:41,144,782 | C/T | intron variant | — |
| rs2253001 | 13:41,145,330 | A/G | — | — |
| rs2755213 | 13:41,146,301 | T/C | intron variant | — |
| rs2721067 | 13:41,156,708 | C/T | intron variant | — |
| rs2701863 | 13:41,170,140 | C/T | regulatory region variant | — |
| rs4943794 | 13:41,173,408 | G/A | — | — |
| rs9549238 | 13:41,179,321 | G/A | intron variant | — |
| rs7985364 | 13:41,179,580 | C/G | intron variant | — |
| rs17061453 | 13:41,184,358 | A/T | intron variant | — |
| rs10507486 | 13:41,186,501 | G/A | regulatory region variant | — |
| rs3900833 | 13:41,188,292 | A/G | upstream gene variant | — |
| rs17630266 | 13:41,194,032 | G/T | coding sequence variant | — |
| rs4941987 | 13:41,195,992 | T/C | downstream gene variant | — |
| rs7323267 | 13:41,204,015 | T/C | regulatory region variant | — |
| rs556463174 | 13:41,204,521 | G/A | — | — |
| rs9532571 | 13:41,218,670 | C/G | — | — |
| rs9549246 | 13:41,220,755 | G/A | intron variant | — |
| rs1334241 | 13:41,223,110 | C/T | intron variant | — |
| rs9577090 | 13:41,225,228 | G/T | — | — |
| rs9549251 | 13:41,228,650 | A/G | intron variant | — |
| rs7324319 | 13:41,233,505 | G/T | — | — |
| rs2297627 | 13:41,233,931 | A/T | — | — |
| rs9549254 | 13:41,234,763 | G/A | intron variant | — |
| rs6563841 | 13:41,239,178 | A/C | regulatory region variant | — |
| rs2501410449 | 13:41,239,868 | C/T | — | pathogenic |
| rs1245991053 | 13:41,239,886 | G/C | — | uncertain significance |
| rs923564490 | 13:41,239,937 | G/A | — | uncertain significance |
| rs947602897 | 13:41,239,972 | C/G | — | likely benign |
| rs1030291335 | 13:41,240,015 | C/A | — | uncertain significance |
| rs1878223078 | 13:41,240,016 | C/A | — | uncertain significance |
| rs1005282881 | 13:41,240,031 | A/G | — | uncertain significance |
| rs963605898 | 13:41,240,039 | C/G | — | likely benign |
| rs2501411593 | 13:41,240,043 | T/G | — | uncertain significance |
| rs2501411704 | 13:41,240,049 | C/T | — | uncertain significance |
| rs1482440466 | 13:41,240,069 | A/C | — | uncertain significance |
| rs2501412134 | 13:41,240,081 | A/C | — | uncertain significance |
| rs1348645141 | 13:41,240,082 | C/G | — | uncertain significance |
| rs1878238580 | 13:41,240,252 | C/G | — | uncertain significance |
| rs1391345095 | 13:41,240,256 | A/C | — | uncertain significance |
| rs542262788 | 13:41,240,296 | G/A | — | likely benign |
Gene information from NCBI Gene. Variant classifications from ClinVar.