Trait
SNPs associated with Osteoarthritis, Hip, Total Hip Arthroplasty
135 genetic variants across 37 genes have been associated with Osteoarthritis, Hip, Total Hip Arthroplasty in published research. Key genes include ACAN, ANKFN1, APOE.
Associated variants135 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs12209223 | — | GWAS association (p=7.0e-58) | Large GWAS |
| rs10843013 | — | GWAS association (p=5.0e-57) | Large GWAS |
| rs1321917 | — | GWAS association (p=3.0e-40) | Large GWAS |
| rs2521349 | MAP2K6 | GWAS association (p=1.0e-36) | Large GWAS |
| rs1046934 | TSEN15 | GWAS association (p=8.0e-35) | Large GWAS |
| rs66989638 | — | GWAS association (p=2.0e-31) | Large GWAS |
| rs28685250 | — | GWAS association (p=3.0e-28) | Large GWAS |
| rs3755384 | TGFA | GWAS association (p=3.0e-26) | Large GWAS |
| rs11750646 | — | GWAS association (p=3.0e-26) | Large GWAS |
| rs2268025 | NEK4 | GWAS association (p=4.0e-26) | Large GWAS |
| rs1591637 | COL11A1 | GWAS association (p=5.0e-26) | Large GWAS |
| rs62576130 | — | GWAS association (p=1.0e-25) | Large GWAS |
| rs2510078 | — | GWAS association (p=1.0e-24) | Large GWAS |
| rs72836447 | — | GWAS association (p=8.0e-24) | Large GWAS |
| rs12210292 | — | GWAS association (p=1.0e-22) | Large GWAS |
| rs13300602 | — | GWAS association (p=3.0e-22) | Large GWAS |
| rs7814941 | GSDMC | GWAS association (p=7.0e-22) | Large GWAS |
| rs28619506 | — | GWAS association (p=3.0e-21) | Large GWAS |
| rs10846653 | — | GWAS association (p=5.0e-21) | Large GWAS |
| rs10797924 | — | GWAS association (p=1.0e-20) | Large GWAS |
| rs80287694 | — | GWAS association (p=4.0e-20) | Large GWAS |
| rs11764536 | — | GWAS association (p=4.0e-20) | Large GWAS |
| rs4507432 | — | GWAS association (p=1.0e-19) | Large GWAS |
| rs76335321 | — | GWAS association (p=1.0e-19) | Large GWAS |
| rs79752115 | — | GWAS association (p=2.0e-18) | Large GWAS |
| rs10518705 | — | GWAS association (p=2.0e-18) | Large GWAS |
| rs1273108 | — | GWAS association (p=3.0e-18) | Large GWAS |
| rs12636716 | — | GWAS association (p=2.0e-17) | Large GWAS |
| rs4252548 | IL11 | GWAS association (p=3.0e-17) | Large GWAS |
| rs9348967 | — | GWAS association (p=3.0e-17) | Large GWAS |
| rs7538503 | — | GWAS association (p=1.0e-16) | Large GWAS |
| rs79514988 | — | GWAS association (p=1.0e-16) | Large GWAS |
| rs9506820 | — | GWAS association (p=1.0e-16) | Large GWAS |
| rs702814 | — | GWAS association (p=2.0e-16) | Large GWAS |
| rs3789870 | TNC | GWAS association (p=3.0e-16) | Large GWAS |
| rs1401451 | — | GWAS association (p=4.0e-16) | Large GWAS |
| rs17817964 | FTO | GWAS association (p=4.0e-16) | Large GWAS |
| rs75686861 | — | GWAS association (p=7.0e-16) | Large GWAS |
| rs11021409 | — | GWAS association (p=7.0e-16) | Large GWAS |
| rs8096658 | — | GWAS association (p=1.0e-15) | Large GWAS |
| rs4709714 | — | GWAS association (p=2.0e-15) | Large GWAS |
| rs11583641 | — | GWAS association (p=5.0e-15) | Large GWAS |
| rs17120227 | — | GWAS association (p=5.0e-15) | Large GWAS |
| rs2205325 | LOC105372740 | GWAS association (p=7.0e-15) | Large GWAS |
| rs76078245 | — | GWAS association (p=3.0e-14) | Large GWAS |
| rs11597888 | EPC1 | GWAS association (p=3.0e-14) | Large GWAS |
| rs2276749 | — | GWAS association (p=3.0e-14) | Large GWAS |
| rs6924424 | BMP6 | GWAS association (p=5.0e-14) | Large GWAS |
| rs7895905 | — | GWAS association (p=6.0e-14) | Large GWAS |
| rs11022512 | TEAD1 | GWAS association (p=1.0e-13) | Large GWAS |
| rs658794 | — | GWAS association (p=2.0e-13) | Large GWAS |
| rs686464 | GASK1A | GWAS association (p=2.0e-13) | Large GWAS |
| rs7020944 | PAPPA | GWAS association (p=2.0e-13) | Large GWAS |
| rs17178530 | — | GWAS association (p=2.0e-13) | Large GWAS |
| rs15691 | TRIOBP | GWAS association (p=7.0e-13) | Large GWAS |
| rs2095140 | — | GWAS association (p=8.0e-13) | Large GWAS |
| rs75621460 | — | GWAS association (p=9.0e-13) | Large GWAS |
| rs975225 | — | GWAS association (p=1.0e-12) | Large GWAS |
| rs1519038 | ERC2 | GWAS association (p=1.0e-12) | Large GWAS |
| rs458465 | — | GWAS association (p=2.0e-12) | Large GWAS |
| rs8078249 | — | GWAS association (p=2.0e-12) | Large GWAS |
| rs9992682 | — | GWAS association (p=2.0e-12) | Large GWAS |
| rs17138874 | — | GWAS association (p=2.0e-12) | Large GWAS |
| rs1999659 | — | GWAS association (p=2.0e-12) | Large GWAS |
| rs67641990 | — | GWAS association (p=3.0e-12) | Large GWAS |
| rs35837782 | — | GWAS association (p=4.0e-12) | Large GWAS |
| rs56155140 | — | GWAS association (p=4.0e-12) | Large GWAS |
| rs10974438 | — | GWAS association (p=4.0e-12) | Large GWAS |
| rs73075492 | — | GWAS association (p=6.0e-12) | Large GWAS |
| rs227729 | — | GWAS association (p=9.0e-12) | Large GWAS |
| rs12578569 | — | GWAS association (p=2.0e-11) | Large GWAS |
| rs1515873 | COL5A2 | GWAS association (p=2.0e-11) | Large GWAS |
| rs7410416 | — | GWAS association (p=3.0e-11) | Large GWAS |
| rs833061 | VEGFA | GWAS association (p=3.0e-11) | Large GWAS |
| rs9892622 | — | GWAS association (p=3.0e-11) | Large GWAS |
| rs13215163 | — | GWAS association (p=3.0e-11) | Large GWAS |
| rs1592795 | ITGA2 | GWAS association (p=4.0e-11) | Large GWAS |
| rs4915735 | NFIA | GWAS association (p=7.0e-11) | Large GWAS |
| rs6020421 | — | GWAS association (p=7.0e-11) | Large GWAS |
| rs1908335 | — | GWAS association (p=7.0e-11) | Large GWAS |
| rs12779973 | — | GWAS association (p=8.0e-11) | Large GWAS |
| rs75495843 | PLCD1 | GWAS association (p=1.0e-10) | Large GWAS |
| rs10047326 | — | GWAS association (p=1.0e-10) | Large GWAS |
| rs1997958 | — | GWAS association (p=1.0e-10) | Large GWAS |
| rs3817428 | ACAN | GWAS association (p=2.0e-10) | Large GWAS |
| rs4074237 | — | GWAS association (p=2.0e-10) | Large GWAS |
| rs4264435 | — | GWAS association (p=2.0e-10) | Large GWAS |
| rs4842708 | — | GWAS association (p=2.0e-10) | Large GWAS |
| rs12040949 | — | GWAS association (p=2.0e-10) | Large GWAS |
| rs12154055 | — | GWAS association (p=2.0e-10) | Large GWAS |
| rs12552028 | COL27A1 | GWAS association (p=2.0e-10) | Large GWAS |
| rs60250748 | FOXO1 | GWAS association (p=3.0e-10) | Large GWAS |
| rs116600817 | — | GWAS association (p=3.0e-10) | Large GWAS |
| rs147786161 | — | GWAS association (p=3.0e-10) | Large GWAS |
| rs55645035 | — | GWAS association (p=4.0e-10) | Large GWAS |
| rs55925606 | — | GWAS association (p=4.0e-10) | Large GWAS |
| rs4021815 | — | GWAS association (p=5.0e-10) | Large GWAS |
| rs13107325 | SLC39A8 | GWAS association (p=5.0e-10) | Large GWAS |
| rs1363608 | — | GWAS association (p=5.0e-10) | Large GWAS |
| rs59015798 | NF1 | GWAS association (p=6.0e-10) | Large GWAS |
Showing the top 100 of 135 variants by evidence strength.
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.