GIGYF1

GRB10 interacting GYF protein 1

Summary

This gene encodes a member of the gyf family of adaptor proteins. The encoded protein contains a gyf protein interaction domain. It binds growth factor receptor bound 10, another adaptor protein that binds activated insulin-like growth factor 1 and insulin receptors and regulates receptor signaling. [provided by RefSeq, Apr 2017]

Known Variants137 total

rsid	Position (GRCh37)	Alleles	Class	ClinVar
rs221790	7:100,278,282	G/A	—	—
rs1163941038	7:100,279,344	A/C	—	pathogenic
rs576725260	7:100,279,356	C/T	—	uncertain significance
rs200959228	7:100,279,363	G/C	—	uncertain significance
rs201843233	7:100,279,376	G/A	—	uncertain significance
rs770926718	7:100,279,377	A/C	—	uncertain significance
rs116169359	7:100,279,402	C/A	—	benign
rs774303622	7:100,279,568	G/A	—	uncertain significance
rs145687446	7:100,279,598	C/T	—	uncertain significance
rs375818199	7:100,279,692	C/T	—	likely benign
rs769314178	7:100,279,705	T/C	—	uncertain significance
rs770178957	7:100,279,709	G/A	—	uncertain significance
rs1452762686	7:100,279,789	C/G	—	uncertain significance
rs2486230140	7:100,279,811	C/T	—	uncertain significance
rs2131367497	7:100,279,819	G/A	—	uncertain significance
rs1325092470	7:100,279,853	T/C	—	uncertain significance
rs200383064	7:100,279,939	G/A	—	likely benign
rs769487907	7:100,279,966	T/C	—	uncertain significance
rs117477530	7:100,279,988	G/A	—	likely benign
rs572372743	7:100,280,005	C/T	—	uncertain significance
rs547530243	7:100,280,011	G/T	—	uncertain significance
rs149825909	7:100,280,070	C/T	—	uncertain significance
rs764497122	7:100,280,071	G/A	—	uncertain significance
rs1278599723	7:100,280,079	C/T	—	uncertain significance
rs771298452	7:100,280,084	C/G	—	likely benign
rs115155006	7:100,280,206	C/T	—	benign
rs749944650	7:100,280,248	G/A	—	likely benign
rs571046762	7:100,280,268	C/T	—	uncertain significance
rs201631397	7:100,280,279	G/A	—	likely benign
rs923825098	7:100,280,282	G/C	—	uncertain significance
rs904006024	7:100,280,337	C/T	—	uncertain significance
rs943342145	7:100,280,644	G/T	—	uncertain significance
rs1272746684	7:100,280,649	G/C	—	uncertain significance
rs755057651	7:100,280,654	T/C	—	uncertain significance
rs748321952	7:100,280,661	G/A	—	uncertain significance
rs777478408	7:100,280,673	G/A	—	uncertain significance
rs770770471	7:100,280,681	G/C	—	uncertain significance
rs2486239391	7:100,280,684	T/C	—	uncertain significance
rs529705193	7:100,280,699	C/T	—	uncertain significance
rs752069062	7:100,280,771	G/C	—	uncertain significance
rs777957103	7:100,280,784	T/G	—	uncertain significance
rs753259209	7:100,280,853	C/T	—	uncertain significance
rs1804976376	7:100,280,935	G/C	—	uncertain significance
rs148785085	7:100,280,938	G/A	—	uncertain significance
rs556905326	7:100,280,965	G/A	—	uncertain significance
rs202101717	7:100,280,994	C/T	—	uncertain significance
rs146891398	7:100,281,048	A/G	—	uncertain significance
rs111254792	7:100,281,221	G/A	—	benign
rs1267710577	7:100,281,232	T/C	—	uncertain significance
rs140997486	7:100,281,468	C/T	—	benign
rs568336617	7:100,281,471	C/A	—	uncertain significance
rs140244722	7:100,281,480	G/C	—	uncertain significance
rs569109894	7:100,281,507	G/A	—	uncertain significance
rs1039418995	7:100,281,512	A/G	—	uncertain significance
rs775340442	7:100,281,515	G/A	—	uncertain significance
rs539867743	7:100,281,518	G/C	—	uncertain significance
rs758421332	7:100,281,661	T/C	—	uncertain significance
rs138722511	7:100,281,681	C/A	—	likely benign
rs2486248744	7:100,281,701	G/A	—	uncertain significance
rs199620213	7:100,281,709	G/A	—	uncertain significance
rs753967563	7:100,281,712	G/A	—	uncertain significance
rs758328622	7:100,281,717	T/C	—	likely benign
rs199733363	7:100,281,723	C/T	—	likely benign
rs769494936	7:100,281,724	G/A	—	uncertain significance
rs1445436777	7:100,281,745	G/A	—	uncertain significance
rs776784807	7:100,281,761	C/T	—	likely benign
rs221794	7:100,281,768	C/T	—	benign
rs775453827	7:100,281,897	G/C	—	uncertain significance
rs1805133580	7:100,282,222	C/G	—	uncertain significance
rs201403082	7:100,282,229	C/T	—	likely benign
rs773630192	7:100,282,352	T/C	—	uncertain significance
rs144129839	7:100,282,381	T/C	—	uncertain significance
rs1185057890	7:100,282,396	T/C	—	uncertain significance
rs760730048	7:100,282,459	G/A	—	uncertain significance
rs759049480	7:100,282,713	C/G	—	uncertain significance
rs201431547	7:100,282,740	C/T	—	uncertain significance
rs199624326	7:100,282,953	T/A	—	likely benign
rs745624568	7:100,282,975	G/A	—	likely benign
rs2486260795	7:100,282,988	T/A	—	likely pathogenic
rs749278992	7:100,282,999	T/G	—	uncertain significance
rs2486261062	7:100,283,020	C/T	—	uncertain significance
rs139769261	7:100,283,025	G/A	—	benign
rs756696255	7:100,283,033	C/T	—	uncertain significance
rs746880791	7:100,283,077	G/A	—	uncertain significance
rs145356671	7:100,283,081	G/A	—	uncertain significance
rs113083799	7:100,283,411	A/G	intron variant	—
rs758579018	7:100,283,608	C/T	—	uncertain significance
rs549384603	7:100,283,844	T/C	—	uncertain significance
rs745925625	7:100,283,885	T/A	—	uncertain significance
rs143725633	7:100,283,914	T/C	—	benign
rs769507990	7:100,283,953	C/G	—	likely benign
rs920549298	7:100,283,970	A/G	—	uncertain significance
rs141450038	7:100,283,987	C/T	—	uncertain significance
rs752373849	7:100,283,989	C/A	—	uncertain significance
rs2486267773	7:100,283,994	C/G	—	uncertain significance
rs138034483	7:100,284,045	G/A	—	uncertain significance
rs1019609332	7:100,284,293	G/A	—	uncertain significance
rs114782558	7:100,284,297	G/A	—	likely benign
rs537109599	7:100,284,300	G/T	—	uncertain significance
rs2131385503	7:100,284,305	G/A	—	likely pathogenic

Showing 100 of 137 variants. Use the SNP search for the full list.

Gene information from NCBI Gene. Variant classifications from ClinVar.