Trait
SNPs associated with Autoimmune Thyroid Disease Susceptibility
100 genetic variants across 37 genes have been associated with Autoimmune Thyroid Disease Susceptibility in published research. Key genes include ADCY7, ARID5B, C1QTNF6.
Associated variants100 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs180223 | TG | Variable association with autoimmune thyroid disease | Meta-analysis |
| rs9272426 | — | GWAS association (p=1.0e-196) | Large GWAS |
| rs2476601 | PTPN22 | GWAS association (p=2.0e-160) | Large GWAS |
| rs3184504 | SH2B3 | GWAS association (p=9.0e-116) | Large GWAS |
| rs925489 | PTCSC2 | GWAS association (p=9.0e-110) | Large GWAS |
| rs231775 | CTLA4 | GWAS association (p=2.0e-74) | Large GWAS |
| rs78765971 | — | GWAS association (p=4.0e-52) | Large GWAS |
| rs654537 | — | GWAS association (p=6.0e-42) | Large GWAS |
| rs7568275 | STAT4 | GWAS association (p=5.0e-39) | Large GWAS |
| rs13080163 | LPP | GWAS association (p=1.0e-37) | Large GWAS |
| rs2757041 | — | GWAS association (p=2.0e-37) | Large GWAS |
| rs71508903 | ARID5B | GWAS association (p=2.0e-31) | Large GWAS |
| rs4409785 | — | GWAS association (p=2.0e-31) | Large GWAS |
| rs229527 | C1QTNF6 | GWAS association (p=3.0e-30) | Large GWAS |
| rs6535628 | LOC107986195 | GWAS association (p=6.0e-30) | Large GWAS |
| rs7090530 | — | GWAS association (p=2.0e-26) | Large GWAS |
| rs3764022 | CLEC2D | GWAS association (p=2.0e-24) | Large GWAS |
| rs76428106 | — | GWAS association (p=2.0e-24) | Large GWAS |
| rs17364832 | — | GWAS association (p=2.0e-23) | Large GWAS |
| rs11052754 | — | GWAS association (p=4.0e-22) | Large GWAS |
| rs11675342 | — | GWAS association (p=1.0e-21) | Large GWAS |
| rs2921071 | — | GWAS association (p=3.0e-21) | Large GWAS |
| rs1534430 | — | GWAS association (p=3.0e-20) | Large GWAS |
| rs4293777 | CLNK | GWAS association (p=2.0e-19) | Large GWAS |
| rs57512118 | — | GWAS association (p=7.0e-19) | Large GWAS |
| rs6914622 | — | GWAS association (p=2.0e-18) | Large GWAS |
| rs7173565 | — | GWAS association (p=9.0e-18) | Large GWAS |
| rs10742340 | SLC1A2 | GWAS association (p=2.0e-17) | Large GWAS |
| rs10686842 | — | GWAS association (p=4.0e-17) | Large GWAS |
| rs2445610 | — | GWAS association (p=1.0e-15) | Large GWAS |
| rs61759532 | — | GWAS association (p=1.0e-15) | Large GWAS |
| rs11079788 | TBX21 | GWAS association (p=3.0e-15) | Large GWAS |
| rs71198528,rs747888955 | — | GWAS association (p=7.0e-15) | Large GWAS |
| rs12582330 | — | GWAS association (p=8.0e-15) | Large GWAS |
| rs76226393 | CLEC2D | GWAS association (p=9.0e-15) | Large GWAS |
| rs1990760 | IFIH1 | GWAS association (p=1.0e-14) | Large GWAS |
| rs7441808 | LINC02357 | GWAS association (p=1.0e-14) | Large GWAS |
| rs9533118 | — | GWAS association (p=1.0e-14) | Large GWAS |
| rs78534766 | ADCY7 | GWAS association (p=1.0e-14) | Large GWAS |
| rs1050976 | — | GWAS association (p=3.0e-14) | Large GWAS |
| rs2123340 | — | GWAS association (p=6.0e-14) | Large GWAS |
| rs244688 | — | GWAS association (p=1.0e-13) | Large GWAS |
| rs34205992 | — | GWAS association (p=1.0e-13) | Large GWAS |
| rs6457834 | — | GWAS association (p=6.0e-13) | Large GWAS |
| rs34536443 | TYK2 | GWAS association (p=8.0e-13) | Large GWAS |
| rs35667974 | IFIH1 | GWAS association (p=9.0e-13) | Large GWAS |
| rs4841567 | — | GWAS association (p=1.0e-12) | Large GWAS |
| rs2069556 | TG | GWAS association (p=1.0e-12) | Large GWAS |
| rs61382221 | — | GWAS association (p=1.0e-12) | Large GWAS |
| rs146750254 | MAGI3 | GWAS association (p=2.0e-12) | Large GWAS |
| rs2745803 | — | GWAS association (p=2.0e-12) | Large GWAS |
| rs6867654 | — | GWAS association (p=3.0e-12) | Large GWAS |
| rs3775291 | TLR3 | GWAS association (p=7.0e-12) | Large GWAS |
| rs301802 | — | GWAS association (p=7.0e-12) | Large GWAS |
| rs10748781 | — | GWAS association (p=8.0e-12) | Large GWAS |
| rs13250295 | — | GWAS association (p=8.0e-12) | Large GWAS |
| rs911760 | — | GWAS association (p=9.0e-12) | Large GWAS |
| rs9494389 | — | GWAS association (p=1.0e-11) | Large GWAS |
| rs202157095 | — | GWAS association (p=1.0e-11) | Large GWAS |
| rs926103 | NTRK1 | GWAS association (p=1.0e-11) | Large GWAS |
| rs9878908 | — | GWAS association (p=1.0e-11) | Large GWAS |
| rs2234167 | TNFRSF14 | GWAS association (p=2.0e-11) | Large GWAS |
| rs12117927 | — | GWAS association (p=2.0e-11) | Large GWAS |
| rs2271194 | ERBB3 | GWAS association (p=2.0e-11) | Large GWAS |
| rs6505765 | — | GWAS association (p=2.0e-11) | Large GWAS |
| rs114378220 | — | GWAS association (p=3.0e-11) | Large GWAS |
| rs7831557 | — | GWAS association (p=3.0e-11) | Large GWAS |
| rs11714843 | — | GWAS association (p=3.0e-11) | Large GWAS |
| rs12697352 | — | GWAS association (p=4.0e-11) | Large GWAS |
| rs3784099 | RAD51B | GWAS association (p=4.0e-11) | Large GWAS |
| rs7251 | IRF3 | GWAS association (p=4.0e-11) | Large GWAS |
| rs1991797 | — | GWAS association (p=5.0e-11) | Large GWAS |
| rs1257920 | — | GWAS association (p=5.0e-11) | Large GWAS |
| rs763361 | CD226 | GWAS association (p=5.0e-11) | Large GWAS |
| rs2823272 | — | GWAS association (p=6.0e-11) | Large GWAS |
| rs2111567 | — | GWAS association (p=1.0e-10) | Large GWAS |
| rs11898293 | — | GWAS association (p=1.0e-10) | Large GWAS |
| rs11720041 | — | GWAS association (p=1.0e-10) | Large GWAS |
| rs61776678 | INPP5B | GWAS association (p=2.0e-10) | Large GWAS |
| rs4320727 | — | GWAS association (p=3.0e-10) | Large GWAS |
| rs1214598 | — | GWAS association (p=3.0e-10) | Large GWAS |
| rs9683415 | — | GWAS association (p=4.0e-10) | Large GWAS |
| rs111352680 | — | GWAS association (p=4.0e-10) | Large GWAS |
| rs7218886 | PIK3R5 | GWAS association (p=4.0e-10) | Large GWAS |
| rs12114596 | RAB2A | GWAS association (p=5.0e-10) | Large GWAS |
| rs72922276 | — | GWAS association (p=5.0e-10) | Large GWAS |
| rs7428218 | — | GWAS association (p=6.0e-10) | Large GWAS |
| rs221796 | GIGYF1 | GWAS association (p=7.0e-10) | Large GWAS |
| rs7758816 | — | GWAS association (p=8.0e-10) | Large GWAS |
| rs1045216 | — | GWAS association (p=8.0e-10) | Large GWAS |
| rs1561924 | LINC00824 | GWAS association (p=8.0e-10) | Large GWAS |
| rs607404 | — | GWAS association (p=1.0e-09) | Large GWAS |
| rs12756886 | GPR25 | GWAS association (p=3.0e-09) | Large GWAS |
| rs7594497 | PNPT1 | GWAS association (p=4.0e-09) | Large GWAS |
| rs1079418 | PDE10A | GWAS association (p=4.0e-09) | Large GWAS |
| rs12793348 | PANX1 | GWAS association (p=5.0e-09) | Large GWAS |
| rs35677470 | DNASE1L3 | GWAS association (p=9.0e-09) | Large GWAS |
| rs1058900 | — | GWAS association (p=9.0e-09) | Large GWAS |
| rs8053655 | TMEM114 | GWAS association (p=2.0e-08) | Large GWAS |
| rs2681417 | — | GWAS association (p=3.0e-08) | Large GWAS |
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.