GPR157
G protein-coupled receptor 157
Summary
Predicted to enable G protein-coupled receptor activity. Predicted to be involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway; phospholipase C-activating G protein-coupled receptor signaling pathway; and radial glial cell differentiation. Predicted to be located in ciliary membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants24 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs554940128 | 1:9,164,543 | C/T | — | uncertain significance |
| rs2521031423 | 1:9,164,557 | G/A | — | uncertain significance |
| rs573584181 | 1:9,164,564 | C/T | — | uncertain significance |
| rs555957933 | 1:9,164,566 | G/C | — | uncertain significance |
| rs2521031867 | 1:9,164,573 | T/C | — | likely benign |
| rs373183983 | 1:9,164,620 | C/T | — | uncertain significance |
| rs767167550 | 1:9,164,630 | C/T | — | uncertain significance |
| rs369928818 | 1:9,164,633 | C/T | — | uncertain significance |
| rs777500057 | 1:9,164,644 | A/G | — | uncertain significance |
| rs1031429559 | 1:9,165,598 | G/C | — | uncertain significance |
| rs772576523 | 1:9,165,606 | C/T | — | uncertain significance |
| rs773700957 | 1:9,165,693 | C/T | — | uncertain significance |
| rs150331624 | 1:9,165,726 | G/C | — | uncertain significance |
| rs1998948 | 1:9,170,937 | T/C | regulatory region variant | — |
| rs2521114346 | 1:9,171,361 | G/T | — | uncertain significance |
| rs201239209 | 1:9,171,414 | G/A | — | uncertain significance |
| rs1638490871 | 1:9,171,436 | G/T | — | uncertain significance |
| rs765736117 | 1:9,171,478 | C/T | — | uncertain significance |
| rs779333690 | 1:9,188,708 | C/A | — | uncertain significance |
| rs2521315571 | 1:9,188,723 | A/G | — | uncertain significance |
| rs759062811 | 1:9,188,746 | C/A | — | uncertain significance |
| rs901471546 | 1:9,188,831 | A/T | — | uncertain significance |
| rs769518688 | 1:9,188,944 | C/G | — | uncertain significance |
| rs1242605752 | 1:9,189,052 | G/C | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.