Trait
SNPs associated with Eye color
124 genetic variants across 20 genes have been associated with Eye color in published research. Key genes include APBA2, EFCAB7, GPR157.
Associated variants124 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs4778218 | OCA2 | GWAS association (p=0.0e+00) | Large GWAS |
| rs1129038 | HERC2 | GWAS association (p=0.0e+00) | Large GWAS |
| rs12203592 | IRF4 | GWAS association (p=2.0e-15) | Large GWAS |
| rs17184180 | LOC105370627 | GWAS association (p=1.0e-284) | Large GWAS |
| rs16891982 | SLC45A2 | GWAS association (p=1.0e-12) | Large GWAS |
| rs1126809 | TYR | GWAS association (p=2.0e-255) | Large GWAS |
| rs13297008 | — | GWAS association (p=5.0e-250) | Large GWAS |
| rs11636232 | HERC2 | GWAS association (p=3.0e-197) | Large GWAS |
| rs7494942 | — | GWAS association (p=4.0e-186) | Large GWAS |
| rs28784029 | HERC2 | GWAS association (p=2.0e-150) | Large GWAS |
| rs111458470 | — | GWAS association (p=3.0e-145) | Large GWAS |
| rs4778241 | OCA2 | GWAS association (p=3.0e-120) | Large GWAS |
| rs2525919 | HERC2 | GWAS association (p=7.0e-97) | Large GWAS |
| rs111433258 | HERC2 | GWAS association (p=2.0e-90) | Large GWAS |
| rs6420484 | TSPAN10 | GWAS association (p=8.0e-90) | Large GWAS |
| rs11324616 | — | GWAS association (p=2.0e-86) | Large GWAS |
| rs7174027 | OCA2 | GWAS association (p=1.0e-85) | Large GWAS |
| rs62330021 | — | GWAS association (p=1.0e-80) | Large GWAS |
| rs138862869 | — | GWAS association (p=3.0e-76) | Large GWAS |
| rs58843292 | — | GWAS association (p=8.0e-67) | Large GWAS |
| rs62007489 | — | GWAS association (p=7.0e-59) | Large GWAS |
| rs34022588 | OCA2 | GWAS association (p=1.0e-55) | Large GWAS |
| rs34823980 | — | GWAS association (p=6.0e-50) | Large GWAS |
| rs622330 | — | GWAS association (p=4.0e-49) | Large GWAS |
| rs373425948 | — | GWAS association (p=3.0e-47) | Large GWAS |
| rs6696511 | — | GWAS association (p=1.0e-45) | Large GWAS |
| rs397854007 | — | GWAS association (p=2.0e-44) | Large GWAS |
| rs869190367 | — | GWAS association (p=4.0e-44) | Large GWAS |
| rs755407864 | — | GWAS association (p=5.0e-44) | Large GWAS |
| rs4778137 | OCA2 | GWAS association (p=7.0e-44) | Large GWAS |
| rs150763518 | — | GWAS association (p=2.0e-43) | Large GWAS |
| rs34369918 | — | GWAS association (p=2.0e-42) | Large GWAS |
| rs4074658 | — | GWAS association (p=3.0e-40) | Large GWAS |
| rs12896399 | LOC105370627 | GWAS association (p=4.0e-38) | Large GWAS |
| rs142046335 | — | GWAS association (p=2.0e-37) | Large GWAS |
| rs117325217 | HERC2 | GWAS association (p=5.0e-37) | Large GWAS |
| rs72714109 | — | GWAS association (p=2.0e-35) | Large GWAS |
| rs11396433 | — | GWAS association (p=7.0e-34) | Large GWAS |
| rs481767 | — | GWAS association (p=8.0e-34) | Large GWAS |
| rs7182377 | OCA2 | GWAS association (p=4.0e-33) | Large GWAS |
| rs56743903 | HERC2 | GWAS association (p=1.0e-32) | Large GWAS |
| rs373468882 | HERC2 | GWAS association (p=2.0e-31) | Large GWAS |
| rs200426972 | — | GWAS association (p=4.0e-31) | Large GWAS |
| rs11365574 | — | GWAS association (p=2.0e-30) | Large GWAS |
| rs111446662 | — | GWAS association (p=6.0e-28) | Large GWAS |
| rs58836608 | — | GWAS association (p=8.0e-28) | Large GWAS |
| rs79743671 | — | GWAS association (p=9.0e-28) | Large GWAS |
| rs9971729 | — | GWAS association (p=5.0e-27) | Large GWAS |
| rs1426654 | SLC24A5 | GWAS association (p=3.0e-26) | Large GWAS |
| rs7161974 | OCA2 | GWAS association (p=5.0e-25) | Large GWAS |
| rs118141530 | HERC2 | GWAS association (p=8.0e-25) | Large GWAS |
| rs7495174 | OCA2 | Brown eye tendency | Large GWAS |
| rs150231163 | HERC2 | GWAS association (p=1.0e-21) | Large GWAS |
| rs2305252 | — | GWAS association (p=3.0e-21) | Large GWAS |
| rs8033755 | HERC2 | GWAS association (p=1.0e-20) | Large GWAS |
| rs533994436 | HERC2 | GWAS association (p=8.0e-20) | Large GWAS |
| rs745333093 | — | GWAS association (p=2.0e-19) | Large GWAS |
| rs148885596 | — | GWAS association (p=3.0e-19) | Large GWAS |
| rs1491544065 | — | GWAS association (p=1.0e-18) | Large GWAS |
| rs117219845 | — | GWAS association (p=2.0e-18) | Large GWAS |
| rs5811535 | — | GWAS association (p=4.0e-18) | Large GWAS |
| rs575299612 | — | GWAS association (p=6.0e-18) | Large GWAS |
| rs112244493 | OCA2 | GWAS association (p=7.0e-18) | Large GWAS |
| rs1408799 | — | GWAS association (p=6.0e-17) | Large GWAS |
| rs746861 | — | GWAS association (p=1.0e-16) | Large GWAS |
| rs28587058 | HERC2 | GWAS association (p=2.0e-16) | Large GWAS |
| rs1847134 | TYR | GWAS association (p=1.0e-15) | Large GWAS |
| rs202126943 | — | GWAS association (p=2.0e-15) | Large GWAS |
| rs146550637 | HERC2 | GWAS association (p=3.0e-15) | Large GWAS |
| rs10960749 | — | GWAS association (p=2.0e-14) | Large GWAS |
| rs140159633 | APBA2 | GWAS association (p=2.0e-14) | Large GWAS |
| rs150568801 | HERC2 | GWAS association (p=7.0e-14) | Large GWAS |
| rs9894429 | NPLOC4 | GWAS association (p=9.0e-14) | Large GWAS |
| rs115000158 | — | GWAS association (p=1.0e-13) | Large GWAS |
| rs4238497 | — | GWAS association (p=7.0e-13) | Large GWAS |
| rs144864205 | HERC2 | GWAS association (p=7.0e-13) | Large GWAS |
| rs150287021 | HERC2 | GWAS association (p=8.0e-13) | Large GWAS |
| rs116879078 | HERC2 | GWAS association (p=1.0e-12) | Large GWAS |
| rs2346098 | HERC2 | GWAS association (p=2.0e-12) | Large GWAS |
| rs1393350 | TYR | Altered eye color | Large GWAS |
| rs17652091 | — | GWAS association (p=3.0e-12) | Large GWAS |
| rs112483884 | HERC2 | GWAS association (p=4.0e-12) | Large GWAS |
| rs111593432 | — | GWAS association (p=8.0e-11) | Large GWAS |
| rs1740397 | EFCAB7 | GWAS association (p=1.0e-10) | Large GWAS |
| rs35409 | — | GWAS association (p=1.0e-10) | Large GWAS |
| rs1003719 | TTC3 | GWAS association (p=2.0e-10) | Large GWAS |
| rs35934407 | — | GWAS association (p=2.0e-10) | Large GWAS |
| rs201911192 | — | GWAS association (p=2.0e-10) | Large GWAS |
| rs2594903 | — | GWAS association (p=2.0e-10) | Large GWAS |
| rs34632582 | — | GWAS association (p=2.0e-10) | Large GWAS |
| rs200980383 | — | GWAS association (p=3.0e-10) | Large GWAS |
| rs1449123735 | HERC2 | GWAS association (p=6.0e-10) | Large GWAS |
| rs1157572508 | — | GWAS association (p=7.0e-10) | Large GWAS |
| rs1998948 | GPR157 | GWAS association (p=1.0e-09) | Large GWAS |
| rs895828 | — | GWAS association (p=1.0e-09) | Large GWAS |
| rs2122005 | — | GWAS association (p=1.0e-09) | Large GWAS |
| rs2856344 | — | GWAS association (p=2.0e-09) | Large GWAS |
| rs849142 | JAZF1 | GWAS association (p=3.0e-09) | Large GWAS |
| rs556360317 | HERC2 | GWAS association (p=3.0e-09) | Large GWAS |
| rs192494731 | HERC2 | GWAS association (p=3.0e-09) | Large GWAS |
Showing the top 100 of 124 variants by evidence strength.
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.