rs1003719
This variant is located in the TTC3 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
eye color
Liu F et al. “Digital quantification of human eye color highlights genetic association of three new loci.” Plos Genetics 6(5):e1000934 (2010)
Allele A
OR 0.10
p 2.0e-10
N 5,951
Large GWAS
European
About TTC3
Enables ubiquitin-protein transferase activity. Involved in protein K48-linked ubiquitination and ubiquitin-dependent protein catabolic process. Located in cytosol; nucleolus; and nucleoplasm. [provided by Alliance of Genome Resources, Jul 2025]
View all TTC3 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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