HPX
hemopexin
Summary
This gene encodes a plasma glycoprotein that binds heme with high affinity. The encoded protein is an acute phase protein that transports heme from the plasma to the liver and may be involved in protecting cells from oxidative stress. [provided by RefSeq, Apr 2009]
Known Variants45 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs149960495 | 11:6,452,454 | C/A | — | uncertain significance |
| rs2493944608 | 11:6,452,532 | A/G | — | uncertain significance |
| rs1590802636 | 11:6,452,555 | C/A | — | uncertain significance |
| rs1849344465 | 11:6,452,567 | A/T | — | uncertain significance |
| rs781573050 | 11:6,452,589 | C/A | — | uncertain significance |
| rs74053382 | 11:6,452,618 | G/A | — | benign |
| rs34557454 | 11:6,452,654 | C/T | — | benign |
| rs2493945000 | 11:6,452,667 | C/T | — | uncertain significance |
| rs150488733 | 11:6,452,695 | G/A | — | uncertain significance |
| rs114914301 | 11:6,452,698 | G/A | — | likely benign |
| rs752887654 | 11:6,452,877 | T/C | — | uncertain significance |
| rs75307540 | 11:6,452,889 | G/A | — | benign |
| rs2493945573 | 11:6,452,949 | T/A | — | likely benign |
| rs73398890 | 11:6,452,953 | G/A | — | benign |
| rs548806193 | 11:6,452,982 | C/T | — | uncertain significance |
| rs17242666 | 11:6,453,332 | T/A | — | — |
| rs187073921 | 11:6,456,265 | C/A | intron variant | — |
| rs146231448 | 11:6,458,299 | T/C | — | uncertain significance |
| rs370184276 | 11:6,458,368 | G/C | — | uncertain significance |
| rs765865106 | 11:6,458,374 | T/C | — | uncertain significance |
| rs748549455 | 11:6,458,709 | G/A | — | uncertain significance |
| rs773537603 | 11:6,458,727 | C/T | — | uncertain significance |
| rs759094687 | 11:6,458,729 | T/C | — | uncertain significance |
| rs139654472 | 11:6,458,751 | G/A | — | uncertain significance |
| rs750261298 | 11:6,458,755 | G/T | — | uncertain significance |
| rs769989807 | 11:6,458,784 | G/A | — | uncertain significance |
| rs34273718 | 11:6,458,839 | C/T | — | benign |
| rs149204852 | 11:6,458,852 | G/A | — | benign |
| rs559750586 | 11:6,458,876 | C/T | — | likely benign |
| rs201618599 | 11:6,458,877 | G/A | — | uncertain significance |
| rs779380990 | 11:6,458,880 | C/G | — | uncertain significance |
| rs780595214 | 11:6,459,717 | G/C | — | uncertain significance |
| rs752160218 | 11:6,459,718 | G/A | — | uncertain significance |
| rs10500670 | 11:6,459,838 | C/T | intron variant | — |
| rs200490788 | 11:6,461,426 | C/T | — | uncertain significance |
| rs955567812 | 11:6,461,450 | G/A | — | uncertain significance |
| rs12117 | 11:6,461,484 | G/A | — | benign |
| rs754589286 | 11:6,461,766 | G/A | — | uncertain significance |
| rs75099526 | 11:6,461,926 | T/C | — | benign |
| rs111378840 | 11:6,462,032 | T/C | regulatory region variant | — |
| rs746524664 | 11:6,462,121 | G/A | — | uncertain significance |
| rs538048682 | 11:6,462,169 | C/T | — | likely benign |
| rs151128069 | 11:6,462,170 | G/A | — | benign |
| rs35899065 | 11:6,462,175 | C/T | — | benign |
| rs59092507 | 11:6,463,155 | C/G | upstream gene variant | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.